Assessing Nanoparticle Risks To Human Health

Author: Gurumurthy Ramachandran
Editor: William Andrew
ISBN: 0323354084
Size: 10,73 MB
Format: PDF, ePub, Mobi
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Assessing Nanoparticle Risks to Human Health provides a systematic overview of nanoparticle risks and considers the limitations of this paradigm in a context where extreme uncertainties prevail. As well as exploring conventional risk assessment methodology, the contributing authors investigate several alternate approaches. The adequacy of current frameworks for risk management and regulatory oversights, including corporate approaches in the US and EU, are explored, and suggestions are made as to how these frameworks can be modified to make them more efficient and effective. Presenting a coherent framework for analysis of the available information, this book presents the latest scientific understanding of the toxicity and health effects of nanoparticles, the technical issues relating to exposure assessment and management, and the ways in which the current risk paradigm can be used/modified to deal with the challenges of nanoparticle risks. All chapters of this new edition have been thoroughly updated to reflect the many changes in the field since the first edition. Additions and updates in the second edition of the book include: New exposure assessment strategies for nanomaterials including life cycle exposure assessment approaches and detailed information on nanoparticle exposure control and protection in the workplace. A state-of-the-art scientific update on the hazard and risk assessment of nanomaterials: discussion of key additional publications on the toxicology and biokinetics of nanomaterials; available data and methods to characterize the health hazard and risk of exposure to nanomaterials in the workplace; additional examples of the use of such data and methods to develop occupational safety and health guidance; and discussion of progress to date, ongoing efforts, and remaining challenges in nanomaterials hazard and risk characterization. New studies on the use of expert judgment in nanotechnology. Quantitative data from Lawrence Berkeley National Laboratory’s 4-phase study. A description and evaluation of new CB tools and new ISO technical specifications. A comprehensive update of the legal frameworks in the US and the EU. With the second edition of Assessing Nanoparticle Risks to Human Health Prof. Ramachandran provides researchers and practitioners producing or using nanoparticles, or those involved in nanomaterials risk assessments, technology, health science, policy, safety, environment and regulatory aspects an invaluable reference to adopt the right technologies and strategies and to comply to legal frameworks and regulations. For policy makers and advisory firms it provides the knowledge needed to advise on compliance with or development of new regulations on nanomaterials. Makes essential reading for risk assessment professionals, companies working with nanoparticles, nanotechnology research groups and regulators Explores the use of risk assessment methodologies in an occupational health setting, and their limitations Provides a framework for evidence-based decision making in a context with many uncertainties

Nanotechnology Environmental Health And Safety

Author: Matthew Hull
Editor: William Andrew
ISBN: 1455731900
Size: 20,73 MB
Format: PDF
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Nanotechnology Environmental Health and Safety, Second Edition focuses not only on the impact of nanotechnology and the discipline of nanotoxicity, but also explains each of these disciplines through in the context of management requirements and via risk scenarios — providing an overview of regulation, risk management, and exposure. Contributors thoroughly explain environmental health and safety (EHS) issues, financial implications, foreseeable risks (e.g., exposure, dose, hazards of nanomaterials), occupational hygiene, and consumer protection. Key new chapters have been included covering eco-toxicity, nanomedicine, informatics, and future threats. New case studies have also been added, including a chapter on the impact of nanosilver on the environment, as well as an assessment of how well lessons have been learned from the past, such as in the case of asbestos. The book also makes a business case for the importance of proactive EHS management - essential reading for existing or prospective producers of nanoscale products. Practical guidance on risk management and mitigation across different legislative frameworks worldwide Reviews toxicological studies and industrial initiatives, supported by numerous case studies Includes extensive new material on the implications of nanotechnology for medicine, energy and food, as well as assessing future threats.

Micromixers

Author: Nam-Trung Nguyen
Editor: William Andrew
ISBN: 1437735215
Size: 16,97 MB
Format: PDF
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The ability to mix minute quantities of fluids is critical in a range of recent and emerging techniques in engineering, chemistry and life sciences, with applications as diverse as inkjet printing, pharmaceutical manufacturing, specialty and hazardous chemical manufacturing, DNA analysis and disease diagnosis. The multidisciplinary nature of this field – intersecting engineering, physics, chemistry, biology, microtechnology and biotechnology – means that the community of engineers and scientists now engaged in developing microfluidic devices has entered the field from a variety of different backgrounds. Micromixers is uniquely comprehensive, in that it deals not only with the problems that are directly related to fluidics as a discipline (aspects such as mass transport, molecular diffusion, electrokinetic phenomena, flow instabilities, etc.) but also with the practical issues of fabricating micomixers and building them into microsystems and lab-on-chip assemblies.With practical applications to the design of systems vital in modern communications, medicine and industry this book has already established itself as a key reference in an emerging and important field. The 2e includes coverage of a broader range of fabrication techniques, additional examples of fully realized devices for each type of micromixer and a substantially extended section on industrial applications, including recent and emerging applications. Introduces the design and applications of micromixers for a broad audience across chemical engineering, electronics and the life sciences, and applications as diverse as lab-on-a-chip, ink jet printing, pharmaceutical manufacturing and DNA analysis Helps engineers and scientists to unlock the potential of micromixers by explaining both the scientific (microfluidics) aspects and the engineering involved in building and using successful microscale systems and devices with micromixers The author's applied approach combines experience-based discussion of the challenges and pitfalls of using micromixers, with proposals for how to overcome them

Ceramic Thick Films For Mems And Microdevices

Author: Robert A. Dorey
Editor: William Andrew
ISBN: 1437778178
Size: 19,52 MB
Format: PDF, Kindle
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The MEMS (Micro Electro-Mechanical Systems) market returned to growth in 2010. The total MEMS market is worth about $6.5 billion, up more than 11 percent from last year and nearly as high as its historic peak in 2007. MEMS devices are used across sectors as diverse as automotive, aerospace, medical, industrial process control, instrumentation and telecommunications - forming the nerve center of products including airbag crash sensors, pressure sensors, biosensors and ink jet printer heads. Part of the MEMS cluster within the Micro & Nano Technologies Series, this book covers the fabrication techniques and applications of thick film piezoelectric micro electromechanical systems (MEMS). It includes examples of applications where the piezoelectric thick films have been used, illustrating how the fabrication process relates to the properties and performance of the resulting device. Other topics include: top-down and bottom-up fabrication of thick film MEMS, integration of thick films with other materials, effect of microstructure on properties, device performance, etc. Provides detailed guidance on the fabrication techniques and applications of thick film MEMS, for engineers and R&D groups. Written by a single author, this book provides a clear, coherently-written guide to this important emerging technology. Covers materials, fabrication and applications in one book.

Nano Size Polymers

Author: Stoyko Fakirov
Editor: Springer
ISBN: 331939715X
Size: 12,81 MB
Format: PDF, ePub, Docs
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This book details all current techniques for converting bulk polymers into nano-size materials. The authors highlight various physical and chemical approaches for preparation of nano-size polymers. They describe the properties of these materials and their extensive potential commercial applications.

Nanotechnology Applications For Clean Water

Author: Anita Street
Editor: William Andrew
ISBN: 1455731854
Size: 20,97 MB
Format: PDF
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Nanotechnology is already having a dramatic impact on improving water quality and the second edition of Nanotechnology Applications for Clean Water highlights both the challenges and the opportunities for nanotechnology to positively influence this area of environmental protection. This book presents detailed information on cutting-edge technologies, current research, and trends that may impact the success and uptake of the applications. Recent advances show that many of the current problems with water quality can be addressed using nanosorbents, nanocatalysts, bioactive nanoparticles, nanostructured catalytic membranes, and nanoparticle enhanced filtration. The book describes these technologies in detail and demonstrates how they can provide clean drinking water in both large scale water treatment plants and in point-of-use systems. In addition, the book addresses the societal factors that may affect widespread acceptance of the applications. Sections are also featured on carbon nanotube arrays and graphene-based sensors for contaminant sensing, nanostructured membranes for water purification, and multifunctional materials in carbon microspheres for the remediation of chlorinated hydrocarbons. Addresses both the technological aspects of delivering clean water supplies and the societal implications that affect take-up Details how the technologies are applied in large-scale water treatment plants and in point-of-use systems Highlights challenges and the opportunities for nanotechnology to positively influence this area of environmental protection

Emerging Nanotechnologies In Dentistry

Author: Karthikeyan Subramani
Editor: William Andrew
ISBN: 1455778621
Size: 18,98 MB
Format: PDF, Mobi
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Nanotechnology and the future of Dentistry -- Nanoparticles for Dental Materials: Synthesis, analysis and Applications -- Antimicrobial nanoparticles in Restorative Composites -- Nanotechnology in operative dentistry: a perspective approach of history, mechanical behavior and clinical application -- Nanotechnology and dental implants -- Titanium surface modification techniques for dental implants - From microscale to nanoscale -- Titanium nanotubes as carriers of osteogenic growth factors and antibacterial drugs for applications in dental implantology -- Cellular responses to nanoscale surface modifications of titanium implants for dentistry and bone tissue engineering applications -- Corrosion Resistance of Ti6Al4V with Nanostructured TiO2 Coatings -- Multiwalled Carbon Nanotubes/Hydroxyapatite Nanoparticles incorporated GTR membranes -- Fabrication of PEG hydrogel micropatterns by Soft-photolithography and PEG hydrogel as Guided Bone Regeneration membrane in dental implantology -- Na ...

Micro And Nanotechnology In Vaccine Development

Author: Mariusz Skwarczynski
Editor: William Andrew
ISBN: 0323400299
Size: 16,90 MB
Format: PDF, Docs
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This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles. Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines

Case Studies In Nanotoxicology And Particle Toxicology

Author: Antonietta M Gatti
Editor: Academic Press
ISBN: 0128012544
Size: 11,10 MB
Format: PDF
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Case Studies in Nanotoxicology and Particle Toxicology presents a highly-illustrated analysis of the most prominent cases on the adverse effects of nanoparticles and their impact on humans and the environment. This comprehensive reference demonstrates the possible risks imposed by managing and handling nanoparticles, showing the effects of involuntary inhalation or ingestion during their use and after their incineration. Through the use of numerous examples, readers will discover the possible risks and effects of working with nanoparticles, along with best practices to prevent these effects. The text is an essential reference for anyone working in the risk assessment of nanoparticles, including nanosafety professionals, occupational toxicologists, regulatory toxicologists, and clinicians. Presents real-life cases showing the potential risks to human health following exposure to nanoparticles An ideal reference for anyone working in the risk assessment of nanoparticles, including nanosafety professionals, occupational toxicologists, regulatory toxicologists, and clinicians Provides examples to help assess risks of handling engineered nanomaterials Advises on the best forms of protection and the safest nanotechnological products

Applied Nanotechnology

Author: Jeremy Ramsden
Editor: William Andrew
ISBN: 0128133449
Size: 10,21 MB
Format: PDF, ePub
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Applied Nanotechnology: The Conversion of Research Results to Products, Third Edition, takes an integrated approach to the scientific, commercial and social aspects of nanotechnology, exploring the relationship between nanotechnology and innovation, the changing economics and business models required to commercialize innovations in nanotechnology, and product design challenges that are investigated through case studies. Applications in various sectors, including composite materials, energy and agriculture are included, as is a section on the role of the government in promoting nanotechnology. In addition, the potential future of molecular self-assembly in industrial production is discussed, along with the ethics and social implications of nanotechnology. This new edition begins a concise introduction to nanotechnology, carefully explaining the relationships between science, technology, wealth and innovation. Next, it focuses on actual products and processes, including the big three areas of application, health, IT and energy. Different types of nanobusiness (upstream, downstream, ancillary etc.), are also carefully delineated, and aspects such as design and realization (e.g., actual fabrication) are also covered, amongst other timely topics. This book offers a vision of the role of nanotechnology in confronting the challenges facing humanity, from healthcare to climate change. Written by an author who has direct, hands-on experience working in a large nanotechnology-based company, in academia as a professor and chair of nanotechnology, and as the co-owner and director of a nanotechnology-based start-up Presents comprehensive coverage in an integrated fashion, not wasting space on trivial details that, if not already known to the reader, can be readily found in generic sources Thoroughly revised, reflecting advances in the field Includes areas that have been expanded into nanotechnology, such as health, and the safety of nano products and processes