Assigning Structures To Ions In Mass Spectrometry

Author: John L. Holmes
Editor: CRC Press
ISBN: 9780203492475
Size: 17,23 MB
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Summarizing our present knowledge of the structures and chemistry of small organic cations in the gas phase, Assigning Structures to Ions in Mass Spectrometry presents the methods necessary for determining gas-phase ion structures. It is a comprehensive resource of background material that is essential for the interpretation and understanding of organic mass spectra. Following a historical introduction of chief discoveries, the book surveys current experimental methods for ion production and separation as well as those designed to reveal qualitative and quantitative aspects of gas-phase ions. It also examines the computational chemistry and theoretical calculations that provide complementary thermochemical, structural, and mechanistic information. Five selected case studies illustrate specific challenges associated with ion structure assignment and thermochemical problems. The last major section of the book contains the data for describing or identifying all ions containing C alone and C with H, O, N, S, P, halogens, and small organic cations. Presenting material written by leading researchers in the field, Assigning Structures to Ions in Mass Spectrometry underscores the importance of understanding the behavior of small organic ions and gas-phase ion chemistry for making new ion structure assignments

Practical Aspects Of Trapped Ion Mass Spectrometry Volume Iv

Author: Raymond E. March
Editor: CRC Press
ISBN: 9781420083729
Size: 16,52 MB
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Reflecting the substantial increase in popularity of quadrupole ion traps and Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometers, Practical Aspects of Trapped Ion Mass Spectrometry, Volume IV: Theory and Instrumentation explores the historical origins of the latest advances in this expanding field. It covers new methods for trapping ions, such as the OrbitrapTM, the digital ion trap (DIT), the rectilinear ion trap (RIT), and the toroidal ion trap; the development and application of the quadrupole ion trap (QIT) and the quadrupole linear ion trap (LIT); and the introduction of high-field asymmetric waveform ion mobility spectrometry (FAIMS). After a combined appreciation and historical survey of mass spectrometry and a discussion of how improved capabilities for microfabrication have led to interest in arrays of ion traps, the book examines the theory and practice of the Orbitrap mass analyzer, the rectangular waveform-driven DIT mass spectrometer, FAIMS, and ion traps with circular geometries. It next discusses ion accumulation for increasing sensitivity in FT-ICR spectrometry, a radio frequency-only-mode event for Penning traps in FT MS, and an FT operating mode applied to a 3D-QIT. The text then presents three behavioral aspects of quadrupole rod sets, before illustrating the development of the 3D-QIT in recent years. The final chapters explore photodissociation in ion traps and the chemical and photochemical studies of metal dication complexes in a 3D-QIT. In this volume that spans twenty-one chapters, a stellar panel of leading experts and up-and-coming researchers presents a cohesive, global, and up-to-date view of the practical aspects of using trapped ion devices. A companion to Volume V: Applications of Ion Trapping Devices, the book authoritatively covers the theory involved as well as the instrumentation currently used in this dynamic field.

Advances In Ion Mobility Mass Spectrometry Fundamentals Instrumentation And Applications

Editor: Elsevier
ISBN: 0444641556
Size: 10,31 MB
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Ion Mobility Spectrometry, Volume 83 will focuses on new trends, methods and instrumentation in the field, starting from the innovations of each technique, to the most progressive challenges of IM-MS. Chapters includes section on Recent advances in IM-MS, IM-MS Principles and Theory, IM-MS Applications and Instrumentation, and the Future of IM-MS. Presents the latest advancements in IM-MS that are essential for new applications Helps readers understand the state-of-the-art in the currently available IM-MS interfaces and their principle uses Provides information on different IM-MS instrumentation Delves into key applications of IM-MS

Mass Spectrometry

Author: M E Rose
Editor: Royal Society of Chemistry
ISBN: 1847556671
Size: 20,16 MB
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Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

Analytical Quality Assurance For Trace Organics Analysis By Gas Chromatography Mass Spectrometry

Author: James W. Eichelberger
Size: 11,82 MB
Format: PDF, ePub
Read: 409

Analyzing Biomolecular Interactions By Mass Spectrometry

Author: Jeroen Kool
Editor: John Wiley & Sons
ISBN: 3527334645
Size: 16,24 MB
Format: PDF, ePub, Docs
Read: 881

This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomics and interactomics. The third and final part discusses other important technologies frequently employed in interaction studies, such as biosensors and microarrays. For pharmaceutical, analytical, protein, environmental and biochemists, as well as those working in pharmaceutical and analytical laboratories.

Interpretation Of Mass Spectra

Author: Fred W. McLafferty
Editor: University Science Books
ISBN: 9780935702255
Size: 15,78 MB
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Published by University Science Books, 20 Edgehill Rd., Mill Valley, CA 94941. The first edition was published more than 25 years ago, the third, in 1980. Automated computer-matching procedures are still only an aid to, not a replacement for, the skilled interpreter; and the path to that skill, as emphasized in every edition of this text, is practice. Annotation copyright by Book News, Inc., Portland, OR

Advances In Physical Organic Chemistry

Editor: Academic Press
ISBN: 0080581471
Size: 11,73 MB
Format: PDF
Read: 173

Advances in Physical Organic Chemistry

Mass Spectrometry In Drug Metabolism And Disposition

Author: Mike S. Lee
Editor: John Wiley & Sons
ISBN: 9780470934692
Size: 13,15 MB
Format: PDF, ePub
Read: 780

This book examines the background, industrial context, process, analytical methodology, and technology of metabolite identification. It emphasizes the applications of metabolite identification in drug research. While primarily a textbook, the book also functions as a comprehensive reference to those in the industry. The authors have worked closely together and combine complementary backgrounds to bring technical and cultural awareness to this very important endeavor while serving to address needs within academia and industry It also contains a variety of problem sets following specific sections in the text.

Lasers And Mass Spectrometry

Author: David M. Lubman
Editor: Oxford University Press
ISBN: 9780195363142
Size: 17,54 MB
Format: PDF, ePub
Read: 272

Contributors to this volume focus on the fundamentals of the technique of analyzing material based on the atomic weight of the species, using the power and definition of lasers to enable measurement of smaller quantities and more finely localized particles. Each chapter deals with a particular application area and should be sufficient to form an entry point for the utilization of mass spectrometry by graduate students and researchers. The book provides the first full discussion of the new techniques of laser applications in the field.