Genetic Analysis

Author: Raphael Falk
Editor: Cambridge University Press
ISBN: 9780521182812
Size: 15,42 MB
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There is a paradox lying at the heart of the study of heredity. To understand the ways in which features are passed on down from one generation to the next, we have to dig deeper and deeper into the ultimate nature of things - from organisms, to genes, to molecules. And yet as we do this, increasingly we find we are out of focus with our subjects. What has any of this to do with the living, breathing organisms with which we started? Organisms are living. Molecules are not. How do we relate one to the other? In Genetic Analysis, one of the most important empirical scientists in the field in the twentieth century attempts, through a study of history and drawing on his own vast experience as a practitioner, to face this paradox head-on. His book offers a deep and innovative understanding of our ways of thinking about heredity.

Genetics And Philosophy

Author: Paul Griffiths
Editor: Cambridge University Press
ISBN: 1107354765
Size: 13,10 MB
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In the past century, nearly all of the biological sciences have been directly affected by discoveries and developments in genetics, a fast-evolving subject with important theoretical dimensions. In this rich and accessible book, Paul Griffiths and Karola Stotz show how the concept of the gene has evolved and diversified across the many fields that make up modern biology. By examining the molecular biology of the 'environment', they situate genetics in the developmental biology of whole organisms, and reveal how the molecular biosciences have undermined the nature/nurture distinction. Their discussion gives full weight to the revolutionary impacts of molecular biology, while rejecting 'genocentrism' and 'reductionism', and brings the topic right up to date with the philosophical implications of the most recent developments in genetics. Their book will be invaluable for those studying the philosophy of biology, genetics and other life sciences.

Was Sind Gene Nicht

Author: Kirsten Schmidt
Editor: transcript Verlag
ISBN: 3839425832
Size: 14,29 MB
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Gene gelten im Allgemeinen als die Essenz eines Lebewesens, die all seine charakteristischen Eigenschaften bestimmt. Aus biologischer Sicht trifft diese Vorstellung jedoch längst nicht mehr zu. Im Mittelpunkt dieses Buches steht daher die Frage, warum und wie das essentialistische Denken die gesellschaftliche Wahrnehmung biologischer Forschungsprojekte immer noch beeinflusst. Anhand aktueller Erkenntnisse der Genetik und Epigenetik geht Kirsten Schmidt auf die Suche nach einer neuen Interpretation des Genbegriffs im Zeitalter der Postgenomik. Das Verständnis von Genen als dynamischen Prozessen erweist sich dabei als eine fruchtbare Alternative zum Essentialismus.

The Gene

Author: Hans-Jörg Rheinberger
Editor: University of Chicago Press
ISBN: 022647478X
Size: 18,15 MB
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Few concepts played a more important role in twentieth-century life sciences than that of the gene. Yet at this moment, the field of genetics is undergoing radical conceptual transformation, and some scientists are questioning the very usefulness of the concept of the gene, arguing instead for more systemic perspectives. The time could not be better, therefore, for Hans-Jörg Rheinberger and Staffan Müller-Wille's magisterial history of the concept of the gene. Though the gene has long been the central organizing theme of biology, both conceptually and as an object of study, Rheinberger and Müller-Wille conclude that we have never even had a universally accepted, stable definition of it. Rather, the concept has been in continual flux—a state that, they contend, is typical of historically important and productive scientific concepts. It is that very openness to change and manipulation, the authors argue, that made it so useful: its very mutability enabled it to be useful while the technologies and approaches used to study and theorize about it changed dramatically.

Enhancing Communication Collaboration In Interdisciplinary Research

Author: Michael O'Rourke
Editor: SAGE Publications
ISBN: 1483323110
Size: 10,59 MB
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Enhancing Communication & Collaboration in Interdisciplinary Research, edited by Michael O'Rourke, Stephen Crowley, Sanford D. Eigenbrode, and J. D. Wulfhorst, is a volume of previously unpublished, state-of-the-art chapters on interdisciplinary communication and collaboration written by leading figures and promising junior scholars in the world of interdisciplinary research, education, and administration. Designed to inform both teaching and research, this innovative book covers the spectrum of interdisciplinary activity, offering a timely emphasis on collaborative interdisciplinary work. The book’s four main parts focus on theoretical perspectives, case studies, communication tools, and institutional perspectives, while a final chapter ties together the various strands that emerge in the book and defines trend-lines and future research questions for those conducting work on interdisciplinary communication.

Thinking About Evolution

Author: Rama S. Singh
Editor: Cambridge University Press
ISBN: 9780521620703
Size: 11,53 MB
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Originally published in 2001, this is the second of two volumes published by Cambridge University Press in honour of Richard Lewontin. This second volume of essays honours the philosophical, historical and political dimensions of his work. It is fitting that the volume covers such a wide range of perspectives on modern biology, given the range of Lewontin's own contributions. He is not just a very successful practitioner of evolutionary genetics, but a rigorous critic of the practices of genetics and evolutionary biology and an articulate analyst of the social, political and economic contexts and consequences of genetic and evolutionary research. The volume begins with an essay by Lewontin on Natural History and Formalism in Evolutionary Genetics, and includes contributions by former students, post-docs, colleagues and collaborators, which cover issues ranging from the history and conceptual foundations of evolutionary biology and genetics, to the implications of human genetic diversity.

Das Egoistische Gen

Author: Richard Dawkins
Editor: Springer-Verlag
ISBN: 3642553915
Size: 10,43 MB
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p”Ein auch heute noch bedeutsamer Klassiker“ Daily Express Sind wir Marionetten unserer Gene? Nach Richard Dawkins ́ vor über 30 Jahren entworfener und heute noch immer provozierender These steuern und dirigieren unsere von Generation zu Generation weitergegebenen Gene uns, um sich selbst zu erhalten. Alle biologischen Organismen dienen somit vor allem dem Überleben und der Unsterblichkeit der Erbanlagen und sind letztlich nur die "Einweg-Behälter" der "egoistischen" Gene. Sind wir Menschen also unserem Gen-Schicksal hilflos ausgeliefert? Dawkins bestreitet dies und macht uns Hoffnung: Seiner Meinung nach sind wir nämlich die einzige Spezies mit der Chance, gegen ihr genetisches Schicksal anzukämpfen.

Das Gen

Author: Siddhartha Mukherjee
Editor:
ISBN: 9783596032358
Size: 11,87 MB
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Biology Computing And The History Of Molecular Sequencing

Author: M. García-Sancho
Editor: Springer
ISBN: 0230370934
Size: 15,82 MB
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Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.

Towards A Theory Of Development

Author: Alessandro Minelli
Editor: OUP Oxford
ISBN: 0191651184
Size: 19,30 MB
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Is it possible to explain and predict the development of living things? What is development? Articulate answers to these seemingly innocuous questions are far from straightforward. To date, no systematic, targeted effort has been made to construct a unifying theory of development. This novel work offers a unique exploration of the foundations of ontogeny by asking how the development of living things should be understood. It explores the key concepts of developmental biology, asks whether general principles of development can be discovered, and examines the role of models and theories. The two editors (one a biologist with long interest in the theoretical aspects of his discipline, the other a philosopher of science who has mainly worked on biological systems) have assembled a team of leading contributors who are representative of the scientific and philosophical community within which a diversity of thoughts are growing, and out of which a theory of development may eventually emerge. They analyse a wealth of approaches to concepts, models and theories of development, such as gene regulatory networks, accounts based on systems biology and on physics of soft matter, the different articulations of evolution and development, symbiont-induced development, as well as the widely discussed concepts of positional information and morphogenetic field, the idea of a 'programme' of development and its critiques, and the long-standing opposition between preformationist and epigenetic conceptions of development. Towards a Theory of Development is primarily aimed at students and researchers in the fields of 'evo-devo', developmental biology, theoretical biology, systems biology, biophysics, and the philosophy of science.