Chirality In Biological Nanospaces

Author: Nilashis Nandi
Editor: CRC Press
ISBN: 1439840024
File Size: 45,78 MB
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Chirality is widely studied and omnipresent in biological molecules. However, how the retention of enantiomeric forms persists in many life processes without racemization is still unclear, and the molecular understanding of the stringent chiral specificity in enzymatic reactions is sparse. An overview of the influence of chirality in driving reactions within enzymatic cavities, Chirality in Biological Nanospaces: Reactions in Active Sites covers: Influences of molecular chirality on the structure of the active site and network of interactions to drive reactions with improved speed, accuracy, and efficiency The conserved features of the organization of the active site structures of enzymes The intricate interplay of electrostatic, hydrophobic, and van der Waals interactions Interactions between the active site residues and the substrate molecules Despite being time-consuming and expensive, trial-and-error is often the primary method used to develop synthetic enzymes. This book describes methods that combine crystallographic studies with electronic structure-based computational analysis. These methods may lead to future elucidation of new drugs that can target biological active sites with better efficacy and can be used to design custom-made novel biocytes with improved efficiency.
Chirality in Biological Nanospaces
Language: en
Pages: 209
Authors: Nilashis Nandi
Categories: Medical
Type: BOOK - Published: 2011-07-27 - Publisher: CRC Press

Chirality is widely studied and omnipresent in biological molecules. However, how the retention of enantiomeric forms persists in many life processes without racemization is still unclear, and the molecular understanding of the stringent chiral specificity in enzymatic reactions is sparse. An overview of the influence of chirality in driving reactions
Chirality in Biological Nanospaces
Language: en
Pages: 209
Authors: Nilashis Nandi
Categories: Medical
Type: BOOK - Published: 2011-07-27 - Publisher: CRC Press

Chirality is widely studied and omnipresent in biological molecules. However, how the retention of enantiomeric forms persists in many life processes without racemization is still unclear, and the molecular understanding of the stringent chiral specificity in enzymatic reactions is sparse. An overview of the influence of chirality in driving reactions
Chirality in Supramolecular Assemblies
Language: en
Pages: 432
Authors: F. Richard Keene
Categories: Science
Type: BOOK - Published: 2017-01-03 - Publisher: John Wiley & Sons

Supramolecular chemistry deals with the organisation of molecules into defined assemblies using non-covalent interactions, including weaker and reversible interactions such as hydrogen bonds, and metal-ligand interactions. The aspect of stereochemistry within such chemical architectures, and in particular chirality, is of special interest as it impacts on considerations of molecular recognition,
Biochirality
Language: en
Pages: 316
Authors: Pedro Cintas
Categories: Science
Type: BOOK - Published: 2014-07-08 - Publisher: Springer

Early History of the Recognition of Molecular Biochirality, by Joseph Gal, Pedro Cintas Synthesis and Chirality of Amino Acids Under Interstellar Conditions, by Chaitanya Giri, Fred Goesmann, Cornelia Meinert, Amanda C. Evans, Uwe J. Meierhenrich Chemical and Physical Models for the Emergence of Biological Homochirality, by son E. Hein, Dragos
Encyclopedia of Biocolloid and Biointerface Science, 2 Volume Set
Language: en
Pages: 1200
Authors: Hiroyuki Ohshima
Categories: Science
Type: BOOK - Published: 2016-09-26 - Publisher: John Wiley & Sons

This encyclopedia uniquely concentrates on biocolloids and biointerfaces rather than the broader field of colloid and interface science. Biocolloids and biointerfaces are the youngest but increasingly prominent studied area of colloid and interface science, and this encyclopedia uses "soft particles" and "soft interface" as surface models in observing phenomena in