Contemporary Phytomedicines

Author: Amritpal Singh Saroya
Editor: CRC Press
ISBN: 1315349949
File Size: 14,59 MB
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The term phytomedicine was coined by French physician Henri Leclerc in 1913. Till recently phytomedicine has remained in the background. But due to emerging challenges to the conventional pharmaceutical industry (cost effectiveness and potency of the drugs), phytomedicine has made a dramatic comeback. Phytomedicine has witnessed several changes and several new concepts have been introduced. Phytomedicine, although, a separate discipline, is strongly linked to Phytotherapy and Phytopharmacology. As the title suggests the book is an attempt to bridge the gap between fundamental and emerging concepts in this field of medicine. The book has been divided into two parts. Part A deals with core issues of the phyto-pharmaceutical drug industry. The book begins with an introductory chapter dealing with basic definitions with phytomedicine. Chapters 2-5 narrate emerging subjects such as Phytopharmacovigilance, Phytopharmacoeconomics, Phytopharmacoepidemiology and Phytopharmacogenomics. Chapter 6 discusses ethical issues in phytomedicine. Chapter 7 covers recent advances in drug delivery systems in phytomedicine whereas Chapter 8 is about application of nanotechnology in the field of phytomedicine. The further chapters cover metabolomics, regulatory and legal aspects of the phyto-pharmaceutical drug industry. The chapter on herbal bioavailability enhancing agents is the salient feature of Part-A. Part B is related to applied research in the field of phytomedicine. Experimental findings on phyto-bioactive agents such as withanolides, steroidal alkaloids, phytosteroids and phytocannabinoids have been elaborated. Nine annexures related to herbal drug registration are included.

Contemporary Phytomedicines

Author: Nisha Dahiya
Editor: Delve Publishing
ISBN: 9781773612850
File Size: 17,99 MB
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Phytomedicine utilizes plants, plant parts or plant derived phytochemical for their medical qualities to prevent or treat various diseases. Natural compounds have been the principle source of lead compounds historically and recently. Plant derived compounds have demonstrated significant activities against a range of diseases including the most deadly diseases such as cancer. Certain compounds possess antimicrobial activities such as chloroform extract of Drosera binate. The extract was found to be bactericidal in in vitro cultures against both planktonic forms and biofilms. The extract acted synergistically with silver nanoparticles resulting in enhancement of antibacterial activity, indi¬cating that the extract alongwith nanoparticles can provide effective alternative to commonly used antibiotics. Coadministering of the leaf extract from Hedera helix L., with existing anti-influenza drug oseltamivir increased the anti-viral activity of oseltamivir at suboptimal doses. The leaf extract which contained hedrasaponin F in highest amount, in combination with oseltamivir decreased pulmonary inflammation in PR8-infected mice, and reduced TNF-alpha and chemokine ligand 2 which are inflammatory cytokine and chemokine. The combination also reduced infiltration of bronchial alveolar of infected mice by CD11b+Ly6G+ and CD11b+Ly6Cint.Natural compounds reportedly have wound healing activity. Liposome formu¬lation of Ligusticum chuanxiong Essential Oil reduced hypertrophic scars on rabbit ears when applied at 2.5, 5 and 10% dosage to the scars for 28 days. Apoptotic markers caspase -3 and -9 levels were significantly increased in the scar tissue, while there was marked decrease in the levels of TGF-?1, MMP-1, collagen I, and collagen III along with the the scar elevation index (SEI). Etha¬nol extract of Mallotus philippinensis bark induces migration of mesenchymal stem cells and improved wound healing in a mouse model and its major compo¬nent cinnamtannin B-1 also augmented migration of mesenchymal cells in vivo and improved wound healing in mice. Silymarin is a mixture of flavonolignane diastereomers found in Silybum mari¬anum extract. Silymarin induces insulin resistance in normal rats at a dose of 200mg/kg and enhanced insulin resistance in rats fed with fructose rich chow. The results indicated that Silymarin may be used for type-2 diabetic patients as it disrupted insulin signaling through increased PTEN expression.A number of extracts have been found to be effective against cancer cell lines in vitro and also in xenograft models. Hydroethanolic Iberis amara extract (IAE) was found to demonstrate anticancerogenic activity against HT-29 and T84 co¬lon carcinoma cells with an inhibitory concentration (IC50) of 6 and 9 ?g/ml respectively and against PC3 prostate cancer and MCF7 breast cancer cell lines. An anti-fungal eugenol, which is derived from the buds of Syzygium aromati¬cum, was demonstrated to interfere with Tat1p and Gap1p permeases which are involved in transport of aromatic and branched chain amino-acids in the yeast cytoplasmic membrane, which may also contribute to amino acid starvation of the cells and maybe used for cancer therapy. Eruthrodiol and Uvaol, naturally occurring triterpenoid alcohols, reduced cell proliferation and affected the cell cycle phases of 1321N astrocytomas (brain cancer cells), along with induction of cell death. Exposure of the cancer cells to Eruthrodiol and Uvaol caused pro¬duction of reactive oxygen species and resulted in loss of mitochondrial trans¬membrane potential and activated the c-jun-N-terminal kinases. Crude extract of Withania somnifera roots when tested against human malignant melanoma A375 cells reduced cell viability, caused nuclear blebbing and DNA fragmenta¬tion indicating its cytotoxic effects on the malignant cells. Certain plant extracts have been demonstrated to have hepatoprotective proper¬ties. Pre-administration of Polydatin, one of the main compounds in Polygo¬num cuspidatum, for 5 days reversed carbon tetrachloride induced liver injury. The effect was evidenced by reversal in the increased serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and hepatic malo¬ndialdehyde (MDA) and expression of hepatic tumor necrosis factor-alpha), interleukin-1 beta (IL-1?), cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS) and nuclearfactor-kappa B (NF-?B). These results confirmed hepatoprotective activity of Polydatin and indicate that it may be used as a candidate for oxidative stress and inflammatory diseases treatment. Plant extract or their derivatives are known to have immune-modulatory prop¬erties. Oenothein B, a polyphenol isolated from Epilobium angustifolium, was demonstrated to stimulate innate and anti-tumor immunity by increasing the production of IFN? alone or along with interleukin-18 in both bovine and hu¬man natural killer cells.

Phytomedicines In Malaria And Sexually Transmitted Diseases

Author: Clement O. Adewunmi
Editor:
ISBN:
File Size: 47,95 MB
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Traditional Knowledge In Contemporary Societies

Author: Kamal Kant Misra
Editor:
ISBN:
File Size: 44,70 MB
Format: PDF, Mobi
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This volume is a modest attempt in this direction. With 26 chapters divided into 5 sections and contributed by anthropologists, activists, botanists, computer scientists, pharmacologists, environmental scientists, and sociologists, this volume is a rich compendium of Indigenous Knowledge research in India and abroad. The sections in the volume focus on theoretical and methodological issues pertaining to Indigenous Knowledge, case studies on the knowledge, case studies on the knowledge of different ethnic, groups, tribal ethno-medical practices, loss of Indigenous Knowledge in social development. The volume is a source book for Indigenous Knowledge research and will be of immense interest to anthropologists, environmental scientists, ethno-botanists, ecologists, computer scientists, sociologists, NGOs and development administrators.

Environmental Challenges Of Contemporary Ethiopia And The Indispensable Role Of Indigenous Trees

Author: Legesse Negash
Editor:
ISBN:
File Size: 74,92 MB
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The Cumulative Book Index

Author:
Editor:
ISBN:
File Size: 24,73 MB
Format: PDF, Docs
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Psychopharmacology Bulletin

Author:
Editor:
ISBN:
File Size: 21,96 MB
Format: PDF, Mobi
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Environmental Health Perspectives

Author:
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ISBN:
File Size: 71,27 MB
Format: PDF, Mobi
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Pharmacology

Author: Joyce LeFever Kee
Editor:
ISBN: 9780721682990
File Size: 10,61 MB
Format: PDF, Mobi
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Fully revised and updated, this clinical pharmacology textbook presents pharmacologic principles in a readily accessible format. It combines pharmacology, drug calculation, and administration for adult and pediatric patients into one comprehensive resource. Drugs are presented in a prototype chart format, providing quick access to generic and brand names, dosages, uses, and considerations, as well as the nursing process in drug therapy. Nearly 100 updated drug charts list dosages, indications, contraindications, drug-lab-food interactions, pharmacokinetics, pharmacodynamics, therapeutic effects, side effects, and adverse reactions. (Includes a FREE SIMON website at:www.harcourthealth.com/SIMON/KeeHayes/pharmacology/)

Social Movements

Author: Dianne Dentice
Editor: Cambridge Scholars Pub
ISBN:
File Size: 33,45 MB
Format: PDF, ePub
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Social movements continue to provide rich fodder for social researchers in the twenty-first century. This reader gives range and depth to ongoing debates about what constitutes a social movement, what motivates actors to participate in social movements, and how social movements continue to evolve in post-industrial societies such as the United States. Not all social movements are about positive social change and some movements have been and will be destructive. The nine essays contained in this text represent classical movements such as the Oneida utopian movement of nineteenth century America and contemporary emerging movements such as the church-growth movement. The authors examine movements that are attempting to revitalize American health care and religious practice along with movements that are counter to social justice such as the white supremacist movement. Was Jonestown a cult or social movement? How does a charismatic leader such as John Humphrey Noyes sell the notion of selective breeding to Oneida communitarians? What is motivating people to participate in the contemporary communal movement in the United States? Such questions are fundamental to our understanding of the emergence and sustainability of social movements. This reader provides authoritative answers to these questions and many more as well as providing a basis for further thought and discussion among students of social movements. While this volume does not attempt to present a unified theory of social movements, the authors apply different theoretical approaches to their explanation of the movements they write about. Authors represent various disciplines such as anthropology, education, and sociology and specialty areas such as criminal justice, immigration, and religion. This multidisciplinary approach adds to the appeal of this reader; with the goal of accessibility to a wide range of audiences who are interested in social movement phenomena, both past and present.

Fundamentals Of Pharmacognosy And Phytotherapy E Book

Author: Michael Heinrich
Editor: Elsevier Health Sciences
ISBN: 0702052310
File Size: 30,39 MB
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‘A new classic’ in a new edition! Fully revised and updated throughout New sections on antimicrobials From journal reviews of the previous edition: ‘Drawing on their wealth of experience and knowledge in this field, the authors, who are without doubt among the finest minds in pharmacognosy today, provide useful and fascinating insights into the history, botany, chemistry, phytotherapy and importance of medicinal plants in some of today's health care systems. This is a landmark textbook, which carefully brings together relevant data from numerous sources and provides in an authoritative and exhaustive manner, cutting edge information that is relevant to pharmacists, pharmacognocists, complementary practitioners, doctors and nurses alike.’ The Pharmaceutical Journal ‘This is the first book that I have encountered which combines the compounds and plants found in standard pharmacognosy textbooks, i.e. those used in orthodox Western medicine, with the 'new phytopharmaceuticals' which have become established in Western culture over the last 20 years. The medical establishment in this environment is finally catching up with the practices of the general population and so this book is an excellent choice for those who wish to investigate which of the many plants available have some scientific credence. I shall be adding this book to the Essential Reading list for all of the undergraduate students on our pharmacy degree course and would encourage all those involved in teaching pharmacy students to do the same." P.J. Houghton, Department of Pharmacy, King's College London, Journal of Ethnopharmacology ‘Educated pharmacists no doubt equate Pharmacognosy with hours spent hunched over a microscope identifying vegetable drugs. Many probably consider it as a subject with little importance in a modern pharmacy curriculum. How wrong they are! ... This book is designed to give an overview at an easy-to-understand level of a broad subject area... For students of science and of the healthcare professions it is a useful text and the authors are to be commended for their work.’ Irish Pharmacy Journal From customer reviews: ‘A new classic. This is an excellent publication both for science students and the non scientific who have an interest in phytotherapy. The layout is logical and clearly set out. I love the chemical structural diagrams, and the explanations of even complex sequences are easy to understand with very little jargon. It is encouraging to see pharmacognosy being given a prominent place in a modern textbook, and interesting to see both hand drawings and chemical structures on the same page!’ ‘I can recommend this to anyone who is interested in the science behind herbal products and medicines; especially if you are interested in plants. It's quite simple to follow and very concise! Good for pharmacy students.’ ‘This is an ultimate textbook in this subject and a boon for students of M Pharmacy (Pharmacognosy) as well as undergraduates students of Pharmacy. Besides them, it is really suitable for every course comprising a study of plants and their medicinal use.’ ‘Excellent reference book. As an editor, I instantly found the answers to various questions I had regarding botanical descriptions. And it even answered questions that I hadn't gotten around to asking. Highly recommended!’

Herbal Companion To Ahfs Di

Author: American Society of Health-System Pharmacists
Editor: Amer Soc of Health System
ISBN:
File Size: 17,38 MB
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"Integrates conventional and alternative medicine, providing evidence-basedmedicine, providing evidence-based monographs of the most common herbal ingredients and nutritional supplements from various schools of healing and health promotion."--Back cover

Quick Access Professional Guide To Conditions Herbs Supplements

Author: Integrative Medicine Communications
Editor: Thieme Medical Pub
ISBN:
File Size: 15,29 MB
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An indispensable source of information that covers both conventional and complementary treatment regimens. Herb monograms give data on the uses, dosages and safety of 36 popular herbs. Supplement monograms provide clinical information on 44 vitamins, minerals, trace elements and amino acids. The guide gives practical guidelines on both conventional and complementary approaches to 100 common conditions.

Medical Malpractice Update

Author:
Editor:
ISBN:
File Size: 27,56 MB
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Fundamentals Of Complementary And Integrative Medicine

Author: Marc S. Micozzi
Editor: Saunders
ISBN:
File Size: 51,81 MB
Format: PDF
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This resource lays the groundwork for a solid understanding of complementary and integrative therapy. It provides insight into the historical context of alternative healing systems, as well as the most up-to-date scientific research and clinical applications for integrative medicine. Focusing on therapies best supported by clinical trials and evidence, it describes key concepts of the most prevalent complementary and alternative therapies in use today. This edition features many new chapters and a new appendix, with thorough updates and references throughout.

Iucn Environmental Policy And Law Paper

Author:
Editor:
ISBN:
File Size: 70,29 MB
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Beyond Miracles

Author: Stephen P. Hersh
Editor: McGraw-Hill/Contemporary
ISBN: 9780809231249
File Size: 43,81 MB
Format: PDF, Kindle
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Provides information and advice to help guide cancer patients through the initial period of devastation that occurs after learning that they have the disease and how to cope with it all

Book Review Index A Master Cumulation 1998 2002

Author:
Editor:
ISBN: 9780787665852
File Size: 42,26 MB
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Sleep Disorders

Author: Herbert Ross
Editor: Alternativemedicine.Com Books
ISBN: 9781887299206
File Size: 31,66 MB
Format: PDF, Mobi
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Addresses the causes of insomnia, restless legs disorder, and sleep apnea, exploring how changes in diet, exercise, natural supplements, and mind/body therapies can provide lasting relief.

Cultural Uses Of Plants

Author: Gabriell DeBear Paye
Editor: New York Botanical Garden PressDept
ISBN:
File Size: 56,56 MB
Format: PDF
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