An Elegant Defense

Author: Matt Richtel
Editor: HarperCollins
ISBN: 0062698508
Size: 15,91 MB
Format: PDF, ePub, Mobi
Read: 572

National Bestseller “One of those rare nonfiction books that transcends the genre. ... Extraordinary.” —Douglas Preston, New York Times bestselling author of The Lost City of the Monkey God A grand tour of the human immune system and the secrets of health, by the Pulitzer Prize–winning New York Times journalist A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before. The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats. For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders. Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance. Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

Summary Study Guide An Elegant Defense

Author: Lee Tang
Editor: LMT Press
ISBN: 1091397279
Size: 11,68 MB
Format: PDF, ePub, Mobi
Read: 637

A Comprehensive Primer on the Human Immune System The must-read summary of “An Elegant Defense: The Extraordinary New Science of the Immune System,” by Matt Richtel. The immune system defends people against germs and microorganisms every day. In most cases, it does a great job of keeping people healthy and preventing infections. But it can easily be compromised by fatigue, stress, toxins, advanced age, and poor nutrition. Problems with the immune system can lead to illness and infection. An unchecked immune system can attack the body's own cells and damage its own organs. Scientists call it autoimmunity, which affects 20 percent of Americans. This book tells you the story of how scientists: * Discover things like T cells and B cells. * Apply their knowledge through life-saving vaccines and transplants. * Delve into the tiny fragments of the immune system and build a blueprint of the machine. * Build medicines by replicating the defense cells. Read this book to better understand one of the enduring mysteries of human biology. This guide includes: * Book Summary—helps you understand the key concepts. * Online Videos—covers the concepts in more depth. Value-added from this guide: * Save time * Understand key concepts * Expand your knowledge

Apolog A De Un Matem Tico

Author: Godfrey Harold Hardy
ISBN: 8412090624
Size: 20,96 MB
Format: PDF, Mobi
Read: 174

G.H. Hardy fue uno de los mejores matemáticos de este siglo, reconocido entre sus contemporáneos como un "matemático auténtico, el más puro entre los puros". Esta Apología, escrita emotivamente cuando su poder creativo matemático estaba ya en su ocaso, es un relato brillante y cautivador de las matemáticas consideradas como mucho más que una ciencia, que nos proporciona una de las mejores visiones de cómo discurre la mente de un matemático en pleno proceso de trabajo. De hecho, este libro está ampliamente considerado como una de las mejores penetraciones en la mente de un matemático profesional, escrita para profanos. En sus páginas, Hardy defiende el valor de la matemática teórica más abstracta y la belleza como valor indispensable de las buenas teorías matemáticas por encima de otros valores como su aplicabilidad o relevancia para los problemas de física. Cuando fue publicada en inglés por primera vez, Graham Greene la aclamó, junto con los cuadernos de notas de Henry James, como "la mejor narración de lo que representa el ser un artista creativo". El prólogo de C. P. Snow a la edición inglesa proporciona algunas claves de la vida de Hardy, incluyendo las anécdotas relativas a su colaboración con el matemático indio Ramanujan, sus aforismos y su pasión por el críquet. Este es un relato único de la fascinación por las matemáticas y de uno de sus exponentes más convincentes de los tiempos modernos.

House Documents

Author: USA House of Representatives
Size: 10,85 MB
Format: PDF, ePub, Mobi
Read: 401

Congressional Series Of United States Public Documents

Size: 10,83 MB
Format: PDF
Read: 772

A Poisoned Life

Author: Richard Jay Hutto
Editor: McFarland
ISBN: 1476670633
Size: 15,95 MB
Format: PDF, ePub, Mobi
Read: 795

"Rick Hutto does a great job of organizing a myriad of facts in this intriguing story of a celebrated miscarriage of justice, and he presents them masterfully as a compelling read."--Mary S. Lovell, author of The Riviera Set: Glitz, Glamour, and the Hidden World of High Society "A scrupulously detailed dissection of one of the most intriguing cases in British judicial history--with a surprising twist at the end."--Anne de Courcy, author of The Viceroy's Daughters: The Lives of the Curzon Sisters Florence Maybrick was the first American woman to be sentenced to death in England--for murdering her husband, a crime she almost certainly did not commit. Her 1889 trial was presided over by an openly misogynist judge who was later declared incompetent and died in an asylum. Hours before Maybrick was to be hanged, Queen Victoria reluctantly commuted her sentence to life in prison--in her opinion a woman who would commit adultery, as Maybrick had admitted, would also kill her husband. Her children were taken from her; she never saw them again. Her mother worked for years to clear her name, enlisting the president of the United States and successive ambassadors, including Robert Todd Lincoln. Decades later, a gruesome diary was discovered that made Maybrick's husband a prime Jack the Ripper suspect.

Cosmopolitanism Ethics In A World Of Strangers Issues Of Our Time

Author: Kwame Anthony Appiah
Editor: W. W. Norton & Company
ISBN: 9780393079715
Size: 11,10 MB
Format: PDF, Docs
Read: 987

“A brilliant and humane philosophy for our confused age.”—Samantha Power, author of A Problem from Hell Drawing on a broad range of disciplines, including history, literature, and philosophy—as well as the author's own experience of life on three continents—Cosmopolitanism is a moral manifesto for a planet we share with more than six billion strangers.

Knowledge And Belief

Author: Frederick F. Schmitt
Editor: Routledge
ISBN: 1134967799
Size: 18,24 MB
Format: PDF
Read: 519

Knowledge, from Plato onwards, has been considered in relation to justified belief. Current debate has centred around the nature of the justification and whether justified belief can be considered an internal or extenal matter. Epistemological internalists argue that the subject must be able to reflect upon a belief to complete the process of justification. The externalists, on the other hand, claim that it is only necessary to consider whether the belief is reliably formed, and argue that the ability to know by reflection is not required for a justified belief. In the historical section of this book the three most important epistemologists, Plato, Descartes and Hume, as well as the ancient epistemologies of the stoics, Academics and Pyrhonians, are considered. In reconsidering the history of epistemology the author is led to argue against hte view that internalism is historically dominant. His critique of internalism is then developed into a sustained argument against many of its forms, and he goes onto defend an externalist, reliabilist epistemology.

Places In Motion

Author: Jacob N. Kinnard
Editor: Oxford University Press
ISBN: 0199359687
Size: 15,11 MB
Format: PDF, Mobi
Read: 298

Jacob Kinnard offers an in-depth examination of the complex dynamics of religiously charged places. Focusing on several important shared and contested pilgrimage places-Ground Zero and Devils Tower in the United States, Ayodhya and Bodhgaya in India, Karbala in Iraq-he poses a number of crucial questions. What and who has made these sites important, and why? How are they shared, and how and why are they contested? What is at stake in their contestation? How are the particular identities of place and space established? How are individual and collective identity intertwined with space and place? Challenging long-accepted, clean divisions of the religious world, Kinnard explores specific instances of the vibrant messiness of religious practice, the multivocality of religious objects, the fluid and hybrid dynamics of religious places, and the shifting and tangled identities of religious actors. He contends that sacred space is a constructed idea: places are not sacred in and of themselves, but are sacred because we make them sacred. As such, they are in perpetual motion, transforming themselves from moment to moment and generation to generation. Places in Motion moves comfortably across and between a variety of historical and cultural settings as well as academic disciplines, providing a deft and sensitive approach to the topic of sacred places, with awareness of political, economic, and social realities as these exist in relation to questions of identity. It is a lively and much needed critical advance in analytical reflections on sacred space and pilgrimage.

David Hume

Author: Russell Hardin
Editor: OUP Oxford
ISBN: 0191610135
Size: 17,41 MB
Format: PDF, Docs
Read: 392

Russell Hardin presents a new explication of David Hume's moral and political theory. With Hume, he holds that our normative views can be scientifically explained but they cannot be justified as true. Hume argued for the psychological basis of such views. In particular, he argued for sympathy as the mirroring of the psychological sensations and emotions of others. By placing Hume in the developing tradition of social science, as a strong forerunner of his younger friend Adam Smith, Hardin demonstrates Hume's strong strategic sense, his nascent utilitarianism, his powerful theory of convention as a main source of social and political order, and his recognition of moral and political theory as a single enterprise.