Glial Neuronal Signaling

Author: Glenn I. Hatton
Editor: Springer Science & Business Media
ISBN: 9781402079368
File Size: 60,26 MB
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Glial Neuronal Signaling fills a need for a monograph/textbook to be used in advanced courses or graduate seminars aimed at exploring glial-neuronal interactions. Even experts in the field will find useful the authoritative summaries of evidence on ion channels and transporters in glia, genes involved in signaling during development, metabolic cross talk and cooperation between astrocytes and neurons, to mention but a few of the timely summaries of a wide range of glial-neuronal interactions. The chapters are written by the top researchers in the field of glial-neuronal signaling, and cover the most current advances in this field. The book will also be of value to the workers in the field of cell biology in general. When we think about the brain we usually think about neurons. Although there are 100 billion neurons in mammalian brain, these cells do not constitute a majority. Quite the contrary, glial cells and other non-neuronal cells are 10-50 times more numerous than neurons. This book is meant to integrate the emerging body of information that has been accumulating, revealing the interactive nature of the brain's two major neural cell types, neurons and glia, in brain function.

Glial Neuronal Signaling In Neuroendocrine Systems

Author: Jeffrey G. Tasker
Editor: Springer Nature
ISBN: 3030623831
File Size: 52,52 MB
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Purinergic Signalling In Neuron Glia Interactions

Author: Derek J. Chadwick
Editor: John Wiley & Sons
ISBN: 0470032235
File Size: 44,51 MB
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ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily diverse organisms. The extracellular biochemistry of ATP and its derivatives is complex, and the multiple membrane receptors that it activates are linked to many intracellular signalling systems. Purinergic signalling affects a diverse range of cellular phenomena, including ion channel function, cytoskeletal dynamics, gene expression, secretion, cell proliferation, differentiation and cell death. Recently, this class of signalling molecules and receptors has been found to mediate communication between neurons and non-neuronal cells (glia) in the central and peripheral nervous systems. Glia are critical for normal brain function, development and response to injury. Neural impulse activity is detected by glia and purinergic signalling is emerging as a major means of integrating functional activity between neurons, glia and vascular cells in the nervous system. These interactions mediate effects of neural activity on the development of the nervous system and in association with injury, neurodegeneration, myelination and cancer. Bringing together contributions from experts in diverse fields, including glial biologists, neurobiologists and specialists in purinergic receptor structure and pharmacology, this book considers how extracellular ATP acts to integrate communication between different types of glia, and between neurons and glia. Beginning with an overview of glia and purinergic signalling, it contains detailed coverage of purine release, receptors and reagents, purinergic signalling in the neural control of glial development, glial involvement in information processing, and discussion of the interactions between neurons and microglia.

Encyclopedia Of Endocrine Diseases

Author: Luciano Martini
Editor: Academic Press
ISBN: 9780124755741
File Size: 66,96 MB
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The Encyclopedia of Endocrine Diseases is an authoritative reference developed by 16 international experts who recruited the world's top scientists for contributions. This stellar reference work focuses on nearly 500 endocrine diseases addressing everything from acromeglay, diabetes, hypertension, osteoporosis, thyroid disease, Von Hippel-Lindau Disease, unexplained weight loss, to androgen related disorders. This encyclopedia is an essential addition to any library collection written to be accessible for both the clinical and non-clinical reader. Associate Editors include: Eli Y. Adashi, John P. Bilezikian, George P. Chrousos, Junichi Fukata, Julianne Imperato-McGinley, Hiroo Imura, Antonio Liuzzi, Frank L. Moore, Daniel Porte, Jens F. Rehfeld, Ellis Samols, Gustav Schonfeld, Pierre C. Sizonenko, Wilmar M. Wiersinga. Also available online via ScienceDirect featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. * Includes nearly 500 entries addressing all aspects of endocrine diseases * More than 800 eminent researchers contributed from 25 different countries around the world * More than 900 figures and 450 tables displayed * Comprehensive glossary comprising 1500 definitions * The Editor-in-Chief is former editor of the journal Frontiers in Neuroendocrinology and has contributed to over 40 books in the field of endocrinology.

Immune And Glial Regulation Of Pain

Author: Joyce A. De Leo
Editor: International Assn for the Study of Pain
ISBN:
File Size: 62,33 MB
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"Review of immune and glial factors within the peripheral and central nervous systems that relate to chronic pain states. Discussion of novel immune and glial targets for clinical pain control that may yield new analgesic drugs"--Provided by publisher.

Glial Cell Receptors

Author: Harold K. Kimelberg
Editor:
ISBN:
File Size: 77,36 MB
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The Journal Of Neuroscience

Author:
Editor:
ISBN:
File Size: 37,96 MB
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The Role Of Glia In Neurotoxicity

Author: Michael Aschner
Editor: CRC Press
ISBN: 9780849347924
File Size: 41,72 MB
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It is well established that glial cells represent more than mere passive cytoskeletal support elements of the central and peripheral nervous system. A reciprocal relationship exists between neurons and glia that is vital for mutual differentiation, development, and functioning of both cell types. It also has become apparent that perturbations in glial function may lead to deleterious consequences in juxtaposed neurons. It is therefore possible that neuronal damage induced by chemicals or neuropathic disease involves dissociation of glial-neuronal interactions. The Role of Glia in Neurotoxicity brings together experts in the neurosciences to provide a more complete understanding of the effects of chemicals on nervous system function. This book explores potential sites of glial-neuronal interactions both in the central and peripheral nervous system, focusing on potential sites of neurotoxicant actions. Text introduces basic aspects of neuroscience, the first step toward understanding the mechanisms at work in normal physiology. The ways in which these processes are disturbed in pathological conditions are discussed. Distinguished authors examine the functional interactions between glial cells and neurons during development, adulthood, and senescence. The roles of glia in the normal CNS and PNS are described. The book offers specific, in-depth examples of directly (via diffusive and cell surface signals) or indirectly (via effects on the extracellular fluid or the blood-brain barrier) mediated glial neurotoxicity. This reference includes different techniques, conceptual frameworks, and approaches that are currently used in the study of the role of glia in neurotoxicity. This timely review not only presents an excellent overview of the state of the science but also provides direction for future research into the consequences of an altered glial-neuronal unit.

Csa Neurosciences Abstracts

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ISBN:
File Size: 37,16 MB
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Molecular Cloning And Functional Characterization Of Axo A Glial Specific Neurexin Like Gene Affecting Neuronal Excitability In Drosophila Melanogaster

Author: Li-Lian Yuan
Editor:
ISBN:
File Size: 46,95 MB
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Mathematical Modeling Of Neuroglial Communication

Author: James Edwards
Editor: VDM Publishing
ISBN:
File Size: 10,17 MB
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Mathematical modelling is being used in many areas of the biological sciences to gain a deeper understanding of the complex mechanisms governing the natural world. No field has more to gain from this type of analysis than the most complex object known, the brain. Glia cells coordinate chemical signalling within the brain. There is great variation in how this is performed, with intercellular communication via gap junctions and extracellular communication via diffusion participating to different degrees within different types of glial cells. Using this as a base, this book draws together existing experimental data and theoretical concepts and develops a new mathematical model that incorporates many aspects of this cellular behaviour. The development of the model is tracked as it is contrasted with other models and applied to a real life scenario. The implementation of the equations into a program is considered and simulation results displayed. The application of the model to real problems is emphasized, though there is consideration of more advanced theoretical concepts for the interested reader."

Modulation Of Astrocyte Neuron Interaction In The Hypothalamus

Author: Adrienne Brooke Cashion
Editor:
ISBN:
File Size: 55,86 MB
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Inositol Homeostasis And Phosphoinositide Signaling During The Neuronal Differentiation Of Nt2 Cells

Author: James Edmund Novak
Editor:
ISBN:
File Size: 10,43 MB
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The Role Of The Nrf2 Antioxidant Response Element Pathway In Neuronal Support Cells During Degeneration

Author: Andrew D. Kraft
Editor:
ISBN:
File Size: 44,59 MB
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Metabotropic Glutamate Receptor Mediated Protection From Glucose Induced Oxidative Injury In Sensory Neurons

Author: Alison Renée Berent-Spillson
Editor:
ISBN:
File Size: 13,27 MB
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Proceedings Of The National Academy Of Sciences Of The United States Of America

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Editor:
ISBN:
File Size: 64,72 MB
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Glial Physiology And Pathophysiology

Author: Alexei Verkhratsky
Editor: John Wiley & Sons
ISBN: 1118402057
File Size: 80,45 MB
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Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells. Coverae includes: the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems the cellular physiology of the different kinds of glial cells the mechanisms of intra- and inter-cellular signalling in glial networks the mechanisms of glial-neuronal communications the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system the cellular and molecular mechanisms of metabolic neuronal-glial interactions the role of glia in nervous system pathology, including pathology of glial cells and associated diseases - for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the 'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it. An up-to-date and fully referenced text on the most numerous cells in the human brain Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system Describes the role og glial cells in neuropathology Focus boxes highlight key points and summarise important facts Companion website with downloadable figures and slides

Rna Editing In Glutamate Receptor Transcripts

Author: Deborah L. Lowe
Editor:
ISBN:
File Size: 58,39 MB
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Advances In Neurology

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Editor:
ISBN:
File Size: 24,12 MB
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The Journal Of Cell Biology

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ISBN:
File Size: 53,85 MB
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No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-