Handbook Of Ion Channels

Author: Jie Zheng
Editor: CRC Press
ISBN: 1466551429
File Size: 41,29 MB
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The New Benchmark for Understanding the Latest Developments of Ion Channels Ion channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of cells. In nonexcitable tissues, they also help regulate basic salt balance critical for homeostasis. All of these features make ion channels important targets for pharmaceuticals. Handbook of Ion Channels illustrates the fundamental importance of these membrane proteins to human health and disease. Renowned researchers from around the world introduce the technical aspects of ion channel research, provide a modern guide to the properties of major ion channels, and present powerful methods for modeling ion channel diseases and performing clinical trials for ion channel drugs. Conveniently divided into five parts, the handbook first describes the basic concepts of permeation and gating mechanisms, balancing classic theories and the latest developments. The second part covers the principles and practical issues of both traditional and new ion channel techniques and their applications to channel research. The third part organizes the material to follow the superfamilies of ion channels. This part focuses on the classification, properties, gating mechanisms, function, and pharmacology of established and novel channel types. The fourth part addresses ion channel regulation as well as trafficking and distribution. The final part examines several ion channel-related diseases, discussing genetics, mechanisms, and pharmaceutical advances.

The Oxford Handbook Of Neuronal Ion Channels

Author:
Editor:
ISBN: 9780190669164
File Size: 23,38 MB
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Handbook Of Receptors And Channels

Author: R. Alan North
Editor: CRC Press
ISBN: 9780849383229
File Size: 69,55 MB
Format: PDF, Docs
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This authoritative and comprehensive volume presents a perspective in the molecular and cellular diversity of membrane ion channels. Written in an accessible format, it depicts the structure and function of each of the known classes of ion channels. Each chapter provides amino acid sequences, including data base accession numbers; views of secondary, tertiary and quaternary channel structure; and evolutionary relationships among channels.

The Oxford Handbook Of The Auditory Brainstem

Author: Karl Kandler
Editor: Oxford University Press, USA
ISBN: 0190849061
File Size: 30,20 MB
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The Oxford Handbook of The Auditory Brainstem provides an introduction as well as an in-depth reference to the organization and function of ascending and descending auditory pathways in the mammalian brainstem. Individual chapters are organized along the auditory pathway beginning with the cochlea and ending with the auditory midbrain. Each chapter provides an introduction to the respective area, and summarizes our current knowledge before discussing disputes and challenges the field currently faces. A major emphasis throughout this book is on the numerous forms of plasticity that are increasingly observed in many areas of the auditory brainstem. Several chapters focus on neuronal modulation of function and synaptic, neuronal, and circuit plasticity, especially under circumstances when they occur most prominently: during development, aging, and following peripheral hearing loss. In addition, the book addresses the role of trauma-induced maladaptive plasticity with respect to its contribution in generating central hearing dysfunction such as hyperacusis and tinnitus. The book is intended for students and postdocs starting in the auditory field, and researchers of related fields who wish to get an authoritative and up-to-date summary of the current state of auditory brainstem research. For clinical practitioners in audiology, otolaryngology, and neurology, the book is a valuable resource of information about the neuronal mechanisms that are major candidates for the generation of central hearing dysfunction.

Handbook Of Cell Signaling

Author: Ralph A. Bradshaw
Editor:
ISBN: 9780121245474
File Size: 58,25 MB
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The Handbook of Cell Signaling is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The subject matter has been divided into five main parts (each of which is headed by a recognized expert in the field): * Initiation: Extracellular and Membrane Events * Transmission: Effectors and Cytosolic Events * Nuclear Responses: Gene Expression and Translation * Events in Intracellular Compartments * Cell-Cell and Cell-Matrix Interactions Covered in extensive detail, these areas will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. Tabular and well-illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field! * Contains approximately 470 articles * Provides well-organized sections on each essential area in signaling * Includes discussion on everything from ligand/receptor interactions to organ/organism responses * Extremely user-friendly.

Handbook Of Electroencephalography And Clinical Neurophysiology Electrical Activity From The Neuron To The Eeg And Emg Pt A Morphological Basis Of Eeg Mechanisms Pt B Basic Neurophysiology Of Neuronal And Glial Potentials Pt C The Neuronal Generation Of The Eeg Pt D Basic Mechanisms Of The Emg

Author: Antoine RĂ©mond
Editor:
ISBN:
File Size: 65,55 MB
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Handbook Of Membrane Channels

Author:
Editor: Academic Press
ISBN: 032313890X
File Size: 21,19 MB
Format: PDF, Kindle
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This handbook provides a thorough account of recent directions in membrane channel research. Each subject is covered in terms of channel biophysics, pharmacology, and molecular biology. The introductory chapter reviews methodologies of molecular biology currently used for studying molecular structure and function of membrane channels and specific domains in channel proteins.

Comparative Physiology

Author: William H. Dantzler
Editor:
ISBN: 9780195074192
File Size: 34,47 MB
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Handbook Of Physiology The Nervous System V 1 Cellular Biology Of Neurons 2 V V 2 Pt 1 2 Motor Control V 3 Pt 1 2 Sensory Processes V 5 Pt 1 2 Higher Functions Of The Brain

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ISBN:
File Size: 11,89 MB
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Handbook Of Multiple Sclerosis

Author: Stuart D. Cook
Editor: Marcel Dekker Incorporated
ISBN:
File Size: 37,46 MB
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Twenty-four essays on major recent advances in the understanding of the genetics, pathophysiology, and immunology of MS including evidence for a viral etiology; evidence for immunopathogenesis; neuroimaging; evoked potentials; and treatment/therapy with monoclonal antibodies, interferon, cyclosporine, corticosteroid, steroids and immunosuppressive drugs, total lymphoid irradiation, plasma exchange and lymphocytapheresis. Annotation(c) 2003 Book News, Inc., Portland, OR (booknews.com)

Handbook Of Local Anesthesia

Author: Stanley F. Malamed
Editor: Mosby Incorporated
ISBN:
File Size: 37,71 MB
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The fifth edition of Handbook of Local Anesthesia is a practical "how-to" guide, updated with the latest advances in science, technology, and pain control techniques. From basic concepts to specific injection techniques, from dosage charts to the proper care and handling of equipment, key information is brought to life with an all-new, full-color design. Written by Dr. Stanley F. Malamed, dentistry's leading expert on this topic, it's a valuable reference that will enhance your practice of local anesthesia. Book jacket.

Handbook Of Physiology

Author: John Richard Pappenheimer
Editor:
ISBN: 9780195074925
File Size: 20,69 MB
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Handbook Of Physiology The Gastrointestinal System V 1 Pt 1 2 Motility And Circulation

Author: American Physiological Society (1887- )
Editor:
ISBN:
File Size: 37,74 MB
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Handbook Of Clinical Anesthesia

Author: Paul G. Barash
Editor: Lippincott Williams & Wilkins
ISBN:
File Size: 78,22 MB
Format: PDF
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This pocket-sized companion to Clinical Anesthesia synthesizes key clinical information in an outline format for easy access to essential information. Many easy-to-read tables, graphs, and appendices are included, as well as a comprehensive drug reference. New in this edition are chapters on anesthesiology for procedures outside the operating room and transplantation, and separate chapters on cancer and acute and chronic pain.

Handbook Of Fluorescent Probes And Research Products

Author: Richard P. Haugland
Editor:
ISBN:
File Size: 45,91 MB
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Molecular And Functional Diversity Of Ion Channels And Receptors

Author: Bernardo Rudy
Editor:
ISBN:
File Size: 45,92 MB
Format: PDF, ePub
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This volume brings together an interdisciplinary group of scientists working with different neurotransmitter receptors and ion channels to discuss how the large amount of information obtained from molecular cloning can be used to advance knowledge of cell and tissue function. It documents the physiological roles of ion channels and receptors, including the functional analysis of subunit composition, role of associated proteins, functional alalysis of native and expressed channels, and physiological and pharmacological investigations of animal models in which specific channels are eliminated or altered.

Handbook Of Clinical Psychopharmacology For Therapists

Author: John Preston
Editor: New Harbinger Publications Incorporated
ISBN:
File Size: 52,13 MB
Format: PDF
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Depression is now the second most-diagnosed ailment in Canada, diagnosed in 9.3 million cases in 2003, an increase of 60 percent since 1995. Adopted for college use, this latest edition includes an update on bipolar disorder and a new chapter on medication and children.

The Immunoassay Handbook

Author: David Wild
Editor:
ISBN: 9781561592708
File Size: 42,50 MB
Format: PDF, ePub
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Offering a unique mix of practical information on immunoassay technology coupled with a review of clinical applications, the Second Edition of this successful reference work is an invaluable source of information. It describes the underlying principles of immunoassay, evaluates major diagnostic products, provides a complete analysis of practical laboratory management, and concludes with an extensive review of immunoassay technology applications in clinical situations. With almost 90 contributing authors, The Immunoassay Handbook offers an authoritative international analysis of contemporary immunoassay.Each of the book's four sections has been expanded and updated from the previous edition: Principles: An overview of the general theory of immunoassay.Products: Details the major diagnostic machinery currently available, outlining features, background theory and development, objective feedback, and comparison between products.Laboratory Management: Including information on sample preparation, quality, troubleshooting, laboratory automation, and laboratory information systems.Applications: of immunoassay technology in clinical situations (which technologies to use in AIDS testing, for example) with theory and background material, as well as key references.Essential reading for clinical chemists and biochemists in medical and biological research laboratories, the Handbook will also be invaluable for marketing and sales staff, and research and development staff at immunoassay manufacturers and distributors. In addition, the book will be useful for students of immunology, biochemistry and medicine.