Thyroid Hormone Receptors

Author: Aria Baniahmad
Editor: Springer Science & Business Media
ISBN: 1592591744
File Size: 37,40 MB
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Because thyroid hormone receptors (TRs) are important regulators of a large number of biological processes-ranging from brain development to control of vision in vertebrates-abnormal functioning of these receptors can have serious medical consequences. In Thyroid Hormone Receptors: Methods and Protocols, a panel of outstanding investigators surveys and explains the major cutting-edge methods used in TR research and their practical experimental details. Described in step-by-step detail to ensure robust experimental results, the techniques presented cover a wide variety of key areas, including TRs in development and generation of knockout (mouse and Xenopus), transcriptional regulation by TRs in both cell-free systems and living cells, and TR mutant analysis of patients. Additional methods provide powerful tools for the isolation of TR-regulated protein complexes, for the study of blood cell differentiation through the oncogene v-erbA, and for target gene analysis in the brain. Microarray chip methods are also presented for analyzing the organs of transgenic mice to identify target genes in the liver. Each protocol has been developed by a hands-on expert and contains full explanatory notes, troubleshooting tips, and helpful comments on avoiding pitfalls. Broad ranging and highly practical, Thyroid Hormone Receptors: Methods and Protocols offers endocrinologists, geneticists, biochemists, and research physicians a comprehensive collection of powerful methods useful not only for all major areas of TR biology and analysis, but also for nuclear hormone receptors in general.
Thyroid Hormone Receptors
Language: en
Pages: 223
Authors: Aria Baniahmad
Categories: Medical
Type: BOOK - Published: 2002 - Publisher: Springer Science & Business Media

Because thyroid hormone receptors (TRs) are important regulators of a large number of biological processes-ranging from brain development to control of vision in vertebrates-abnormal functioning of these receptors can have serious medical consequences. In Thyroid Hormone Receptors: Methods and Protocols, a panel of outstanding investigators surveys and explains the major
Plant Hormone Receptors
Language: en
Pages: 319
Authors: Dieter Klämbt
Categories: Science
Type: BOOK - Published: 2013-06-29 - Publisher: Springer Science & Business Media

The Nato Advanced Research Workshop on Plant Hormone Receptors was held at the Physik Zentrum in Bad Honnef near Bonn, August 18-22, 1986. This workshop was mainly supported by the Nato Scientific Affairs Division and additionally cosponsered by Hoechst AG, Frankfurt and BASF AG, Ludwigshafen. The workshop aimed at focusing
Molecular Biology of Steroid and Nuclear Hormone Receptors
Language: en
Pages: 319
Authors: Leonard Freedman
Categories: Science
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

Intracellular Receptors: New Instruments for a Symphony of Signals In the late eighteenth century, it was proposed on theoretical grounds that each of the body's organs, beginning with the brain, must be "a factory and laboratory of a specific humor which it returns to the blood", and that these circulating
Clinical Interest of Steroid Hormone Receptors in Breast Cancer
Language: en
Pages: 351
Authors: G. Leclercq, S. Toma, R. Paridaens, J. C. Heuson
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

Several papers dealing with the clinical relevance of steroid hormone receptors in breast cancer have already been published. However, no publication has overviewed studies currently being conducted in Europe, nor is there a register of the european centers performing receptor assays. It has been our purpose to fill these gaps.
Steroid Hormone Receptors: Basic and Clinical Aspects
Language: en
Pages: 522
Authors: V. K. Moudgil
Categories: Medical
Type: BOOK - Published: 2012-11-25 - Publisher: Birkhäuser

The past few years have witnessed the emergence of steroid hormones as the wonder molecules which generate as much discussion in the scientific literature as they do in a typical living room. This transition has been a result of the tremendous public and scientific interest in the normal functioning of