Selection In One And Two Locus Systems

Author: T. Nagylaki
Editor: Springer Science & Business Media
ISBN: 3642930611
File Size: 35,85 MB
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Most of these notes were presented as part of a two-quarter course on theoretical population genetics at The University of Chicago. Almost all the students were either undergraduates in mathematics or graduate students in the biological sciences. The only prerequisites were calculus and matrices. As is done in these notes, biological background and additional mathematical techniques were covered when they were required. I have included the relevant problems assigned in the course. My aim in these notes is to formulate the various models fairly generally, making the biological assumptions quite explicit, and to perform the analyses relatively rigorously. I hope the choice and treatment of topics will enable the reader to understand and evaluate detailed analyses of specific models and applications in the literature. No attempt has been made to review the literature or to assign credit. Most of the references are to papers directly germane to the subjects and approaches covered here. Frequency of reference is not intended to reflect proportionate contribution. I am very grateful to Professor James F. Crow for helpful comments and to Mrs. Adelaide Jaffe for her excellent typing. I thank the National Science Foundation for its support (Grant No. DEB76-01550).
Selection in One- and Two-Locus Systems
Language: en
Pages: 210
Authors: T. Nagylaki
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

Most of these notes were presented as part of a two-quarter course on theoretical population genetics at The University of Chicago. Almost all the students were either undergraduates in mathematics or graduate students in the biological sciences. The only prerequisites were calculus and matrices. As is done in these notes,
Evolution and Selection of Quantitative Traits
Language: en
Pages: 1504
Authors: Bruce Walsh, Michael Lynch
Categories: Science
Type: BOOK - Published: 2018-06-21 - Publisher: Oxford University Press

Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters
Introduction to Theoretical Population Genetics
Language: en
Pages: 369
Authors: Thomas Nagylaki
Categories: Science
Type: BOOK - Published: 2013-03-12 - Publisher: Springer Science & Business Media

This book covers those areas of theoretical population genetics that can be investigated rigorously by elementary mathematical methods. I have tried to formulate the various models fairly generally and to state the biological as sumptions quite explicitly. I hope the choice and treatment of topics will en able the reader
Handbook of Statistical Genetics
Language: en
Pages: 1616
Authors: David J. Balding, Martin Bishop, Chris Cannings
Categories: Science
Type: BOOK - Published: 2008-06-10 - Publisher: John Wiley & Sons

The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past three years. In particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. As a consequence the 3rd edition of the
Evolution in Age-Structured Populations
Language: en
Pages: 306
Authors: Brian Charlesworth
Categories: Mathematics
Type: BOOK - Published: 1994-06-30 - Publisher: Cambridge University Press

Examines theories and methods used to study age-structured populations.