Role Of Cancer Stem Cells In Cancer Biology And Therapy

Author: Thomas Dittmar
Editor: CRC Press
ISBN: 1466577363
File Size: 73,24 MB
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This book summarizes the latest findings about the role of cancer stem cells (CSCs) in cancer biology and how this knowledge could be used for novel anticancer therapies. It provides an overview of CSCs in selected malignancies with particular emphasis on hematopoietic neoplasias. It then reviews the role of CSCs in metastasis formation and initiation of cancer relapses. It also examines the dark side of cancer therapy such as conventional cancer therapies that may lead to the origin of recurrence CSCs. Finally, it supplies a brief overview of current concepts that may allow for a selective eradication of CSCs.
Role of Cancer Stem Cells in Cancer Biology and Therapy
Language: en
Pages: 332
Authors: Thomas Dittmar, Kurt S. Zänker
Categories: Medical
Type: BOOK - Published: 2016-04-19 - Publisher: CRC Press

This book summarizes the latest findings about the role of cancer stem cells (CSCs) in cancer biology and how this knowledge could be used for novel anticancer therapies. It provides an overview of CSCs in selected malignancies with particular emphasis on hematopoietic neoplasias. It then reviews the role of CSCs
Stem Cells and Cancer Stem Cells,Volume 3
Language: en
Pages: 400
Authors: M.A. Hayat
Categories: Medical
Type: BOOK - Published: 2011-11-22 - Publisher: Springer Science & Business Media

It is pointed out that cancer stem cell is a cell type within a tumor that possesses the capacity of cell-renewal and can give rise to the heterogeneous lineages of cancer cells that comprise the tumor. It is emphasized that a cancer stem cell is a tumor initiating cell. That
Stem Cells and Cancer Stem Cells, Volume 4
Language: en
Pages: 319
Authors: M.A. Hayat
Categories: Medical
Type: BOOK - Published: 2012-02-09 - Publisher: Springer Science & Business Media

Vast therapeutic applications of the following specific stem cells in disease and tissue injury are discussed: embryonic stem cells, induced pluripotent stem cells, human hair follicle stem cells, bone marrow-derived human mesenchymal stem cells, adipose-derived stem cells, periodontal/progenitor cells, cancer stem cells, and breast cancer stem cells. Because human embryonic
Stem Cells and Cancer Stem Cells, Volume 1
Language: en
Pages: 200
Authors: M.A. Hayat
Categories: Medical
Type: BOOK - Published: 2011-10-12 - Publisher: Springer Science & Business Media

Difference between tissue specific stem cells and embryonic stem cells is explained. The advantages of the latter are included. The application of human pluripotent stem cells, mesenchymal stem cells, and hematopoietic stem cells in cancer therapy and tissue/organ regeneration is detailed. Role of neural cancer stem cells in brain tumors,
Stem Cells and Cancer Stem Cells, Volume 5
Language: en
Pages: 309
Authors: M.A. Hayat
Categories: Medical
Type: BOOK - Published: 2012-02-21 - Publisher: Springer Science & Business Media

It is pointed out that a cancer stem cell is a type within a tumor that possesses the capacity of self-renewal and can give rise to the heterogeneous lineages of cancer cells, which comprise the tumor. It is emphasized that a unique feature of cancer stem cells is that, although