Advances In Swine In Biomedical Research

Author: L.B. Schook
Editor: Springer Science & Business Media
ISBN: 1461558859
File Size: 57,77 MB
Format: PDF, Kindle
Read: 9151
Download

Similarities in structure and function between pigs and human beings include size, feeding patterns, digestive physiology, dietary habits, kidney structure and function, pulmo nary vascular bed structure, coronary artery distribution, propensity to obesity, respiratory rates, tidal volumes and social behaviors. Since the pig is an omnivore, it provides an adaptable model to evaluate chronic and acute exposures to xenobiotics such as alcohoL caffeine, tobacco, food additives and environmental pollutants. Swine have been used successfully as models to evaluate alcoholism, diabetes, absorption, digestion, total paren teral nutrition, organ transplantation, atherosclerosis, exercise, hypertension. hemorrhagic hypotension, melanoma, gingivitis, obstructive and reflux nephropathy. osteochondrosis. dermal healing and septic shock. A severe and worsening shortage of organs and tissues for transplantation in patients with severe organ failure has encouraged the consideration of inter species or xenotransplan tation. In developing programs toward this end, the pig generally is viewed as the preferred donor because of its size, physiology and availability. The pig harbors relatively few diseases which could be transmitted inadvertently to human patients. The ability to genetically modify swine to ameliorate the consequences of the human immune response offers a further significant advantage. Another important consideration for an animal model is that basic biologic back ground information be available for investigators to design future prospective studies.

Animal Models In Biomedical Research

Author: Cynthia Petrie Smith
Editor:
ISBN:
File Size: 65,98 MB
Format: PDF, ePub, Docs
Read: 6936
Download


Sourcebook Of Models For Biomedical Research

Author: P. Michael Conn
Editor: Springer Science & Business Media
ISBN: 1588299333
File Size: 30,53 MB
Format: PDF, Mobi
Read: 5166
Download

The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

Animal Welfare Information Center Bulletin

Author:
Editor:
ISBN:
File Size: 76,40 MB
Format: PDF, Mobi
Read: 5309
Download


The Minipig In Biomedical Research

Author: Peter A. McAnulty
Editor: CRC Press
ISBN: 1439811199
File Size: 65,84 MB
Format: PDF, Mobi
Read: 2636
Download

The Minipig in Biomedical Research is a comprehensive resource for research scientists on the potential and use of the minipig in basic and applied biomedical research, and the development of drugs and chemicals. Written by acknowledged experts in the field, and drawing on the authors’ global contacts and experience with regulatory authorities and the pharmaceutical and other industries, this accessible manual ranges widely over the biological, scientific, and practical uses of the minipig in the laboratory. Its coverage extends from the minipig’s origins, anatomy, genetics, immunology, and physiology to its welfare, health, and husbandry; practical dosing and examination procedures; surgical techniques; and all areas of toxicity testing and the uses of the minipig as a disease model. Regulatory aspects of its use are considered. The reader will find an extensive amount of theoretical and practical information in the pharmacology; ADME and toxicology chapters which will help scientists and managers when deciding which species to use in basic research; drug discovery and pharmacology; and toxicology studies of chemicals, biotechnology products and devices. The book discusses regulatory uses of minipigs in the evaluation of human and veterinary pharmaceuticals, medical devices, and other classes of xenobiotics. It describes features of normal health, normal laboratory values, and common diseases. It also carefully elucidates ethical and legal considerations in their supply, housing, and transport. The result is an all-inclusive and up to date manual about the experimental uses of the minipig that describes ‘How to’ and ‘Why’ and ’What to expect in the normal’, combining enthusiasm and experience with critical assessment of its values and potential problems.

Animal Models For Biomedical Research

Author: Institute of Laboratory Animal Resources (U.S.)
Editor: National Academy Press
ISBN:
File Size: 47,25 MB
Format: PDF
Read: 3719
Download


Special Reference Briefs

Author:
Editor:
ISBN:
File Size: 51,15 MB
Format: PDF, Mobi
Read: 7063
Download


Swine In The Laboratory

Author: M. Michael Swindle
Editor: CRC Press
ISBN: 9781420009156
File Size: 47,30 MB
Format: PDF, ePub
Read: 8447
Download

To diminish the learning curve associated with using swine as models, Swine in the Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition provides practical technical information for the use of swine in biomedical research. The book focuses on models produced by surgical and other invasive procedures, supplying the ba

Swine In Cardiovascular Research

Author: Hubert C. Stanton
Editor: CRC
ISBN:
File Size: 42,33 MB
Format: PDF, ePub
Read: 5771
Download


International Symposium Swine In Biomedical Research

Author:
Editor:
ISBN:
File Size: 15,85 MB
Format: PDF, Mobi
Read: 3969
Download


Biomedical Index To Phs Supported Research

Author:
Editor:
ISBN:
File Size: 54,34 MB
Format: PDF, ePub, Docs
Read: 8318
Download


Animal Models For Nutrition Research

Author:
Editor:
ISBN:
File Size: 76,60 MB
Format: PDF, Docs
Read: 9423
Download


Laboratory Animal Science

Author:
Editor:
ISBN:
File Size: 60,57 MB
Format: PDF, ePub, Docs
Read: 5731
Download


Animal Quality And Models In Biomedical Research

Author: International Council for Laboratory Animal Science
Editor: Gustav Fischer
ISBN:
File Size: 36,19 MB
Format: PDF, Mobi
Read: 2843
Download


Periodicum Biologorum

Author:
Editor:
ISBN:
File Size: 73,47 MB
Format: PDF
Read: 9610
Download


Veterinary Clinical Pathology

Author:
Editor:
ISBN:
File Size: 66,93 MB
Format: PDF, ePub, Mobi
Read: 8812
Download


Comparative Medicine

Author:
Editor:
ISBN:
File Size: 29,11 MB
Format: PDF, ePub, Mobi
Read: 3339
Download


Proceedings Of The Society For Experimental Biology And Medicine

Author: Society for Experimental Biology and Medicine (New York, N.Y.)
Editor:
ISBN:
File Size: 18,42 MB
Format: PDF, ePub
Read: 2609
Download

List of members in each volume