The Fundamentals Of Modern Statistical Genetics

Author: Nan M. Laird
Editor: Springer Science & Business Media
ISBN: 9781441973382
File Size: 29,62 MB
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This book covers the statistical models and methods that are used to understand human genetics, following the historical and recent developments of human genetics. Starting with Mendel’s first experiments to genome-wide association studies, the book describes how genetic information can be incorporated into statistical models to discover disease genes. All commonly used approaches in statistical genetics (e.g. aggregation analysis, segregation, linkage analysis, etc), are used, but the focus of the book is modern approaches to association analysis. Numerous examples illustrate key points throughout the text, both of Mendelian and complex genetic disorders. The intended audience is statisticians, biostatisticians, epidemiologists and quantitatively- oriented geneticists and health scientists wanting to learn about statistical methods for genetic analysis, whether to better analyze genetic data, or to pursue research in methodology. A background in intermediate level statistical methods is required. The authors include few mathematical derivations, and the exercises provide problems for students with a broad range of skill levels. No background in genetics is assumed.

Heterogeneity In Statistical Genetics

Author: Derek Gordon
Editor: Springer Nature
ISBN: 3030611213
File Size: 14,32 MB
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Quantitative Genetics And Its Connections With Big Data And Sequenced Genomes

Author: Charles J Mode
Editor: World Scientific Publishing Company
ISBN: 9813140704
File Size: 14,26 MB
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The book gives an overview of developments in Quantitative Genetics and variance component analysis in an era of Big Data and Sequenced Genomes. It provides a detailed description of a direct method of estimation that will be a useful means of extracting information from a large set of data that was inconceivable 10 to 20 years ago. The book is a combination of a history of variance component analysis and a forward looking view as to how direct methods of estimation arise from the availability of big data sets and sequenced genomes of each individual in the sample. Many papers and books on quantitative genetics versions of the general linear model from statistics are useful for analyzing the data, using relatively small sets of data. In this book, new methods of direct estimation are introduced and analyzed that are appropriate for an era of big sets of data and sequences genomes. These direct methods of estimation are based on taking conditional expectations rather the methods of least squares that characterize many applications of the general linear model of statistics. Request Inspection Copy

Compositional Data Analysis

Author: Josep Antoni Martín-Fernández
Editor: Springer
ISBN: 3319448110
File Size: 46,30 MB
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The authoritative contributions gathered in this volume reflect the state of the art in compositional data analysis (CoDa). The respective chapters cover all aspects of CoDa, ranging from mathematical theory, statistical methods and techniques to its broad range of applications in geochemistry, the life sciences and other disciplines. The selected and peer-reviewed papers were originally presented at the 6th International Workshop on Compositional Data Analysis, CoDaWork 2015, held in L’Escala (Girona), Spain. Compositional data is defined as vectors of positive components and constant sum, and, more generally, all those vectors representing parts of a whole which only carry relative information. Examples of compositional data can be found in many different fields such as geology, chemistry, economics, medicine, ecology and sociology. As most of the classical statistical techniques are incoherent on compositions, in the 1980s John Aitchison proposed the log-ratio approach to CoDa. This became the foundation of modern CoDa, which is now based on a specific geometric structure for the simplex, an appropriate representation of the sample space of compositional data. The International Workshops on Compositional Data Analysis offer a vital discussion forum for researchers and practitioners concerned with the statistical treatment and modelling of compositional data or other constrained data sets and the interpretation of models and their applications. The goal of the workshops is to summarize and share recent developments, and to identify important lines of future research.

Developmental Psychopathology Developmental Neuroscience

Author: Dante Cicchetti
Editor: John Wiley & Sons
ISBN: 1118120914
File Size: 62,46 MB
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The complete reference of biological bases for psychopathology at any age Developmental Psychopathology is a four-volume compendium of the most complete and current research on every aspect of the field. Volume Two: Developmental Neuroscience focuses on the biological basis of psychopathology at each life stage, from nutritional deficiencies to genetics to functional brain development to evolutionary perspectives and more. Now in its third edition, this comprehensive reference has been fully updated to better reflect the current state of the field, and detail the newest findings made possible by advances in technology and neuroscience. Contributions from expert researchers and clinicians provide insight into brain development, molecular genetics methods, neurogenics approaches to pathway mapping, structural neuroimaging, and much more, including targeted discussions of specific disorders. Advances in developmental psychopathology have burgeoned since the 2006 publication of the second edition, and keeping up on the latest findings in multiple avenues of investigation can be burdensome to the busy professional. This series solves the problem by collecting the information into one place, with a logical organization designed for easy reference. Consider evolutionary perspectives in developmental psychopathology Explore typical and atypical brain development across the life span Examine the latest findings on stress, schizophrenia, anxiety, and more Learn how genetics are related to psychopathology at different life stages The complexity of a field as diverse as developmental psychopathology deepens with each emerging theory, especially with consideration of the rapid pace of neuroscience advancement and genetic discovery. Developmental Psychopathology Volume Two: Developmental Neuroscience provides an invaluable resource by compiling the latest information into a cohesive, broad-reaching reference.

Technometrics

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Book Review Index

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Every 3rd issue is a quarterly cumulation.

Fundamentals Of Genetics

Author: Peter J. Russell
Editor: Harpercollins College Division
ISBN:
File Size: 34,32 MB
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Gives full coverage of genetics, including the step-by-step problem-solving approach pioneered by the author. The book is suitable for students who have a limited background in biology and chemistry, or for briefer courses where there is little time to cover advanced topics.

Which Degree In Britain

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A comprehensive guide to full-time degree courses, institutions and towns in Britain.

Statistical Genetics

Author: Prem Narain
Editor: Wiley
ISBN: 9780470213971
File Size: 63,63 MB
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Describes the methodology of statistical genetics, especially with respect to plant and animal breeding. Introduces the principles of Mendelian genetics and discusses population and quantitative genetics. Emphasizes how statistical principles help in understanding the genetic gains expected by efficient methods of selection and breeding, as well as indicating the techniques of analysis of breeding data. Includes numerous tables of breeding data for quick reference.

Fundamentals Of Probability A First Course

Author: Anirban DasGupta
Editor: Springer Science & Business Media
ISBN: 1441957804
File Size: 14,72 MB
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Probability theory is one branch of mathematics that is simultaneously deep and immediately applicable in diverse areas of human endeavor. It is as fundamental as calculus. Calculus explains the external world, and probability theory helps predict a lot of it. In addition, problems in probability theory have an innate appeal, and the answers are often structured and strikingly beautiful. A solid background in probability theory and probability models will become increasingly more useful in the twenty-?rst century, as dif?cult new problems emerge, that will require more sophisticated models and analysis. Thisisa text onthe fundamentalsof thetheoryofprobabilityat anundergraduate or ?rst-year graduate level for students in science, engineering,and economics. The only mathematical background required is knowledge of univariate and multiva- ate calculus and basic linear algebra. The book covers all of the standard topics in basic probability, such as combinatorial probability, discrete and continuous distributions, moment generating functions, fundamental probability inequalities, the central limit theorem, and joint and conditional distributions of discrete and continuous random variables. But it also has some unique features and a forwa- looking feel.

Western Reserve University Bulletin

Author: Western Reserve University
Editor:
ISBN:
File Size: 52,80 MB
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Beginning 19 - each bulletin contains details of curricula, course description, college rules, etc., for one of the schools or colleges at Western Reserve University.

Which Degree

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File Size: 63,84 MB
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Fundamentals Of Ecology

Author: Eugene Pleasants Odum
Editor: Brooks/Cole Publishing Company
ISBN:
File Size: 14,61 MB
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Master the study of ecology in the twenty-first century with FUNDAMENTALS OF ECOLOGY! Designed to educate a wide audience about ecological science, this biology text shows you the application of ecological principles in the real world and how to use what you learn to solve problems in fields such as resource management, conservation biology, ecological toxicology, ecosystem health, landscape ecology, and restoration ecology. Introductory statements, diagrams, models, photographs, and a book-specific website are just a few of the tools found throughout the text that will help you succeed.

The Science In Modern Living Series

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File Size: 55,49 MB
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Empire Cotton Growing Review

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Cotton Growing Review

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File Size: 65,21 MB
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Modern Psychometrics

Author: John Rust
Editor:
ISBN:
File Size: 58,84 MB
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The new edition of this classic text has been completely revised and updated, taking into account recent developments in the field of psychometrics. The book fulfils the requirements of those studying for BPS certificates of competence in testing.