The Gut Microbiome In Health And Disease

Author: Dirk Haller
Editor: Springer
ISBN: 3319905457
Size: 20,25 MB
Format: PDF, ePub, Docs
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The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

The Gut Microbiome In Health And Disease

Author: Nathan W. Schmidt
Editor: Frontiers Media SA
ISBN: 288963003X
Size: 18,38 MB
Format: PDF, Mobi
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Xenobiotics And The Gut Microbiome In Health And Disease

Author: Stephen J. Pandol
Editor: Frontiers Media SA
ISBN: 288963082X
Size: 15,37 MB
Format: PDF, Docs
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Health And The Gut

Author: William Olds
Editor: CRC Press
ISBN: 1498701264
Size: 15,70 MB
Format: PDF, Kindle
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This title includes a number of Open Access chapters. The study of the intestinal ecosystem of bacteria in the human gut—the gut microbiome—is a new field that is rapidly evolving. This book serves as an introduction to some of the new and exciting research that is being done in this field. Included are chapters that examine the following: • Gut microbiome’s roles in the pathogenesis of obesity and autoimmune disease • The effect of nutrition on the richness of the microbial community • The stability of the microbiome to various stressors • Emerging ways to diagnose diseases using the microbiome • Exciting prospects for using these microbes to cure disease This easily accessible reference volume offers a comprehensive guide to this relatively new field of study. Edited by a researcher from Yale University, Health and the Gut: The Emerging Role of Intestinal Microbiota in Disease and Therapeutics is an authoritative and easy-to-use reference, ideal for both researchers in the field and those who wish to gain more information about the impact of gut microbiota on human health.

Microbiota In Health And Disease From Pregnancy To Childhood

Author: Pamela D. Browne
Editor: Wageningen Academic Publishers
ISBN: 9086868398
Size: 10,61 MB
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This book offers a state-of-the-art overview of the vital relationship between human microbiota and infant and child health. Renowned clinical-experimental experts in this field discuss the development of microbiota during early life and review the environmental inputs that affect the developing infant’s gut microbiota, such as early diet and (postnatal) medical interventions. They further describe the interplay between gut microbiota and functional systems of the body, from the immune system to the central nervous system. The book discusses a range of infant and childhood diseases that are associated with microbial changes or dysbiosis, such as gastrointestinal disorders, allergic diseases, autoimmune disorders and respiratory disorders. Additionally mechanisms by which microbial dysbiosis may influence behaviour in infants are discussed. Other topics include the use of current tools in molecular microbiology for microbiota-related research and clinical practice. In the management of particular paediatric disorders, the potential of microbial manipulation with pre- and probiotics during infancy and childhood is increasingly being investigated. This book presents the evidence supporting their use in practice and reviews safety aspects. Microbiota in health and disease: from pregnancy to childhood has the ambition to provide the reader with an overview of the most recent and stunning advances in the field of infant and child microbiota and their role in health, disease and prevention. As such, it is an excellent resource for health care professionals, students and researchers in the field of life sciences.

The Human Microbiota And Microbiome

Author: Julian R Marchesi
Editor: CABI
ISBN: 1780640498
Size: 18,66 MB
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Thousands of different microbial species colonize the human body, and are essential for our survival. This book presents a review of the current understanding of human microbiomes, the functions that they bring to the host, how we can model them, their role in health and disease and the methods used to explore them. Current research into areas such as the long-term effect of antibiotics makes this a subject of considerable interest. This title is essential reading for researchers and students of microbiology.

Diet Microbe Interactions In The Gut

Author: Kieran Tuohy
Editor: Academic Press
ISBN: 0124079415
Size: 13,17 MB
Format: PDF, Docs
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Drawing on expert opinions from the fields of nutrition, gut microbiology, mammalian physiology, and immunology, Diet-Microbe Interactions for Human Health investigates the evidence for a unified disease mechanism working through the gut and its resident microbiota, and linking many inflammation-related chronic diet associated diseases. State of the art post-genomic studies can highlight the important role played by our resident intestinal microbiota in determining human health and disease. Many chronic human diseases associated with modern lifestyles and diets — including those localized to the intestinal tract like inflammatory bowel disease and celiac disease, and more pervasive systemic conditions such as obesity, diabetes and cardiovascular disease — are characterized by aberrant profiles of gut bacteria or their metabolites. Many of these diseases have an inflammatory basis, often presenting with a chronic low-grade systemic inflammation, hinting at persistent and inappropriate activation of inflammatory pathways. Through the presentation and analysis of recent nutrition studies, this book discusses the possible mechanisms underpinning the disease processes associated with these pathologies, with high fat diets appearing to predispose to disease, and biologically active plant components, mainly fiber and polyphenols, appearing to reduce the risk of chronic disease development. One comprehensive, translational source for all aspects of nutrition and diet's effect on gastrointestinal health and disease Experts in nutrition, diet, microbiology and immunology take readers from the bench research (cellular and biochemical mechanisms of vitamins and nutrients) to new preventive and therapeutic approaches Clear presentations by leading researchers of the cellular mechanisms underlying diet, immune response, and gastrointestinal disease help practicing nutritionists and clinicians (gastroenterologists, endocrinologists) map out new areas for clinical research and structuring clinical recommendations

Metabonomics And Gut Microbiota In Nutrition And Disease

Author: Sunil Kochhar
Editor: Springer
ISBN: 144716539X
Size: 11,54 MB
Format: PDF, ePub, Docs
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This book provides a comprehensive overview of metabonomics and gut microbiota research from molecular analysis to population-based global health considerations. The topics include the discussion of the applications in relation to metabonomics and gut microbiota in nutritional research, in health and disease and a review of future therapeutical, nutraceutical and clinical applications. It also examines the translatability of systems biology approaches into applied clinical research and to patient health and nutrition. The rise in multifactorial disorders, the lack of understanding of the molecular processes at play and the needs for disease prediction in asymptomatic conditions are some of the many questions that system biology approaches are well suited to address. Achieving this goal lies in our ability to model and understand the complex web of interactions between genetics, metabolism, environmental factors and gut microbiota. Being the most densely populated microbial ecosystem on earth, gut microbiota co-evolved as a key component of human biology, essentially extending the physiological definition of humans. Major advances in microbiome research have shown that the contribution of the intestinal microbiota to the overall health status of the host has been so far underestimated. Human host gut microbial interaction is one of the most significant human health considerations of the present day with relevance for both prevention of disease via microbiota-oriented environmental protection as well as strategies for new therapeutic approaches using microbiota as targets and/or biomarkers. In many aspects, humans are not a complete and fully healthy organism without their appropriate microbiological components. Increasingly, scientific evidence identifies gut microbiota as a key biological interface between human genetics and environmental conditions encompassing nutrition. Microbiota dysbiosis or variation in metabolic activity has been associated with metabolic deregulation (e.g. obesity, inflammatory bowel disease), disease risk factor (e.g. coronary heart disease) and even the aetiology of various pathologies (e.g. autism, cancer), although causal role into impaired metabolism still needs to be established. Metabonomics and Gut Microbiota in Nutrition and Disease serves as a handbook for postgraduate students, researchers in life sciences or health sciences, scientists in academic and industrial environments working in application areas as diverse as health, disease, nutrition, microbial research and human clinical medicine.

Human Microbiota In Health And Disease

Author: Bryan Tungland
Editor: Academic Press
ISBN: 0128146508
Size: 17,95 MB
Format: PDF, Kindle
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Human Gut Microbiota in Health and Disease: From Pathogenesis to Therapy is a comprehensive discussion on all the aspects associated with the early colonization of gut microbiota, its development and maintenance, and its symbiotic relationship with the host in promoting health. Chapters illustrate the complex mechanisms and metabolic signaling pathways related to how the gut microbiota maintain proper regulation of glucose, lipid and energy homeostasis and immune response, all while mediating inflammatory processes involved in the etiology of many chronic disease conditions. With today's common use of pharmaceutical medicine in treating symptoms and frequent overuse of antibiotics in chronic disease within mainstream medical practice, our understanding of the etiological mechanisms of dysbiosis-induced chronic disease and natural approaches to prevention and potential cures for these diseases is of vital importance to overall human health. Details the complex relationship between human microbiota in the gut, oral cavity and skin as well as their colonization, development and impact of factors that influence the relationship Illustrates the mechanisms associated with dysbiosis-associated inflammation and its role in the onset and progression in chronic disease Provides the primary mechanisms and comprehensive scientific evidence for the use of dietary modification and pro- and prebiotics in preventing chronic disease

Gut Microbiota

Author: Edward Ishiguro
Editor: Academic Press
ISBN: 0128105429
Size: 13,67 MB
Format: PDF
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Gut Microbiota: Interactive Effects on Nutrition and Health provides a detailed account of gut microbiota research, an exploration of how diet influences gut microbiota and the implications of gut microbiota for health. The book provides a summary of how diet interacts with the gut microbiome and presents practical applications focused on food, supplements and safety. This book provides scientists and clinicians who have an interest in the microbiome with an understanding of the future potential—and limitations—of this tool, as they strive to make use of evidence-based diet information for the maintenance of good health. Consolidates new research on how gut microbiota affects nutrition Identifies how the research applies to food, supplements and safety Provides diet recommendations to improve health Includes case studies from clinical populations Explores how diet influences gut microbiota