The Hedgehog Handbook

Author: Sally Coulthard
Editor: Head of Zeus Ltd
ISBN: 178854112X
Size: 16,10 MB
Format: PDF, Docs
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Hedgehogs, with their quiet determination and bristling, bumbling ways, are seen by many of one of life's most enduring symbols of the countryside and town gardens. This shy, snuffling, enigmatic animal has captured the imagination of children and adults for centuries – from Beatrix Potter's Mrs Tiggywinkle to Sonic the Hedgehog. Full to the brim with fascinating insights and countryside lore, The Hedgehog Handbook explores different facets of this much-admired mammal – from its wildlife habits to its literary heritage, how different cultures have viewed the hedgehog and what we can do to help preserve this icon of rural life. Fun, sweet and warm hearted, The Hedgehog Handbook is a month by month celebration of one of the countryside's best-loved creatures. Packed with inspirational quotes, entertaining facts, folklore and literary references, it's the perfect gift for anyone with a penchant for prickles.

Handbook Of Anticancer Pharmacokinetics And Pharmacodynamics

Author: Michelle A. Rudek
Editor: Springer Science & Business Media
ISBN: 1461491355
Size: 14,53 MB
Format: PDF, ePub, Mobi
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There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer. Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs. Road map to anticancer drug development from discovery to NDA submission Discussion of molecular targets and preclinical screening Development and validation of bioanalytical methods Chapters on clinical trial design and phase 0, I, II, III clinical trials Pharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agents Review of the drug development process from both laboratory and clinical perspectives New technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development

2020 2021 Oncology Nursing Drug Handbook

Author: Gail M. Wilkes
Editor: Jones & Bartlett Learning
ISBN: 1284171329
Size: 20,93 MB
Format: PDF
Read: 394
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Written especially for nurses caring for patients with cancer, the 2020-2021 Oncology Nursing Drug Handbook uniquely expresses drug therapy in terms of the nursing process: nursing diagnoses, etiologies of toxicities, and key points for nursing assessment, intervention, and evaluation. Updated annually, this essential reference provides valuable information on effective symptom management, patient education, and chemotherapy administration. Completely revised and updated, the 2018 Oncology Nursing Drug Handbook includes separate chapters on molecular and immunologic/biologic targeted therapies. These chapters provide fundamental reviews to assist nurses in understanding the cellular communication pathways disrupted by cancer. It also offers simplified content, attention to understanding the immune checkpoint inhibitors, new information about immunotherapy, new drugs and their indications, and updated indications and side effects for recently FDA approved drugs.

2017 Oncology Nursing Drug Handbook

Author: Wilkes
Editor: Jones & Bartlett Learning
ISBN: 1284117189
Size: 15,30 MB
Format: PDF, ePub, Docs
Read: 671
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Written especially for nurses caring for patients with cancer, the 2017 Oncology Nursing Drug Handbook uniquely expresses drug therapy in terms of the nursing process: nursing diagnoses, etiologies of toxicities, and key points for nursing assessment, intervention, and evaluation. Updated annually, this essential reference provides valuable information on effective symptom management, patient education, and chemotherapy administration. Completely revised and updated, the 2017 Oncology Nursing Drug Handbook includes separate chapters on molecular and immunologic/biologic targeted therapies. These chapters provide fundamental reviews to assist nurses in understanding the cellular communication pathways disrupted by cancer. It also offers simplified content, attention to understanding the immune checkpoint inhibitors, new information about immunotherapy, new drugs and their indications, and updated indications and side effects for recently FDA approved drugs. New drugs include: alectin

The Bee Bible

Author: Sally Coulthard
Editor: Head of Zeus Ltd
ISBN: 1788545826
Size: 12,87 MB
Format: PDF, Mobi
Read: 526
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We need bees. We rely on them not only to pollinate our planet but to sweeten our lives with the fruits of their labours – honey, beeswax, Royal Jelly. These tiny, hardworking insects have transformed our lives with their quiet diligence; fertilising much of our food, most of the wild plants we rely on, and giving us thousands of years of sugary pleasure, candlelight and beauty treatments. But bees are in danger. Across the planet, bee numbers are plummeting. Honey bees, fat, fluffy bumblebees and key species of solitary bees are disappearing from our gardens, fields and wild spaces. Over the past 50 years, the UK has lost more than half its solitary bee numbers and three species of bumblebee have gone extinct. In the rest of Europe, nearly one in ten species of wild bees are facing extinction, in the US about a quarter of all wild bees have disappeared in the past ten years alone. Thankfully, we can do something if we act now. In The Bee Bible, best-selling author Sally Coulthard shows us fifty positive ways we can all save bees; from planting flowers bees love to mowing less, buying the right honey to influencing public spaces and government policy. Whether you garden for bees, shop with bees in mind, campaign for bees, or just learn a bit of bee-whispering, little things can make a big difference. Just ask a bee.

The Contemporary History Handbook

Author: Brian Brivati
Editor: Manchester University Press
ISBN: 9780719048364
Size: 11,73 MB
Format: PDF, ePub
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This guide should be useful to those studying and researching modern history. International and up to date, it covers sources and controversies in the subject area and includes a section of useful addresses. The volume is divided into three main sections which together comprise a reference work for contemporary historians.

A Handbook Of Weather Folk Lore

Author: Charles Swainson
Editor:
ISBN:
Size: 11,83 MB
Format: PDF, Kindle
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The long-awaited prophecy surrounding Percy Jackson's sixteenth birthday unfolds as he leads an army of young demigods to stop Kronos in his advance on New York City, while the Olympians struggle to contain the rampaging monster, Typhon.

A Handbook Of Weather Folk Lore Being A Collection Of Proverbiat Sayings In Varions Languages Relating To The Wheather

Author: Charles Swainson
Editor:
ISBN:
Size: 19,27 MB
Format: PDF, Docs
Read: 794
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The Wiley Blackwell Handbook Of Infant Development Volume 2

Author: J. Gavin Bremner
Editor: John Wiley & Sons
ISBN: 1444332740
Size: 13,21 MB
Format: PDF, ePub
Read: 141
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Now part of a two-volume set, the fully revised and updated second edition of The Wiley-Blackwell Handbook of Infant Development, Volume 2: Applied and Policy Issues provides comprehensive coverage of the applied and policy issues relating to infant development. Updated, fully-revised and expanded, this two-volume set presents in-depth and cutting edge coverage of both basic and applied developmental issues during infancy Features contributions by leading international researchers and practitioners in the field that reflect the most current theories and research findings Includes editor commentary and analysis to synthesize the material and provide further insight The most comprehensive work available in this dynamic and rapidly growing field

Handbook Of Orthodontics E Book

Author: Martyn T. Cobourne
Editor: Elsevier Health Sciences
ISBN: 0723436037
Size: 10,62 MB
Format: PDF
Read: 809
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Richly illustrated and in full colour throughout, the new HANDBOOK OF ORTHODONTICS presents the subject of orthodontics in an accessible, easy-to-read manner. Whilst maintaining a strong clinical focus throughout, this new volume provides the reader with a firm understanding of the problem of malocclusion and its management and addresses the controversies in modern orthodontics by taking an evidence-based look at current clinical practice. The book also presents a clear explanation of the basic sciences of relevance to the orthodontist, including an up-to-date look at craniofacial development, growth and syndromic conditions that affect this region. Offers comprehensive coverage of clinical orthodontics, from diagnosis and treatment planning through contemporary removable and fixed appliances to cleft lip and palate Helps the reader develop a critical approach to the different philosophies of treatment by addressing controversies in orthodontics and looking at current clinical practice in an evidence-based manner Covers the scientific basis of orthodontics in detail with particular focus on embryology, craniofacial development, growth and the biology of tooth movement Numerous clinical examples clearly illustrate the theory described Succinct writing style and rich use of pedagogy - almost 400 illustrations and tables together with ‘pull-out boxes’ – to help make learning easy Ideal for use as a textbook or as a reference manual Suitable for senior dental students, postgraduate trainees and residents in orthodontics