The Mathematics And Mechanics Of Biological Growth

Author: Alain Goriely
Editor: Springer
ISBN: 038787710X
File Size: 18,23 MB
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This monograph presents a general mathematical theory for biological growth. It provides both a conceptual and a technical foundation for the understanding and analysis of problems arising in biology and physiology. The theory and methods are illustrated on a wide range of examples and applications. A process of extreme complexity, growth plays a fundamental role in many biological processes and is considered to be the hallmark of life itself. Its description has been one of the fundamental problems of life sciences, but until recently, it has not attracted much attention from mathematicians, physicists, and engineers. The author herein presents the first major technical monograph on the problem of growth since D’Arcy Wentworth Thompson’s 1917 book On Growth and Form. The emphasis of the book is on the proper mathematical formulation of growth kinematics and mechanics. Accordingly, the discussion proceeds in order of complexity and the book is divided into five parts. First, a general introduction on the problem of growth from a historical perspective is given. Then, basic concepts are introduced within the context of growth in filamentary structures. These ideas are then generalized to surfaces and membranes and eventually to the general case of volumetric growth. The book concludes with a discussion of open problems and outstanding challenges. Thoughtfully written and richly illustrated to be accessible to readers of varying interests and background, the text will appeal to life scientists, biophysicists, biomedical engineers, and applied mathematicians alike.

Morpho Elasticity

Author: Alain Goriely
Editor: Springer
ISBN: 9780387877617
File Size: 10,90 MB
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Growth plays a fundamental role in many biological processes and is considered to be the hallmark of life itself. It is a process of extreme complexity and its description has been one of the fundamental problems of life sciences. However, until recently, it has not attracted much attention from mathematicians, physicists, and mechanicians. The goal of this monograph is to present the state of knowledge in the mechanics of growth, to provide a rigorous foundation and, to offer a set of mathematical tools for the analysis of specific problems arising in biology accessible to mathematicians, physicists, and biologists. Simple examples, applications and building discussions are included. The emphasis of the book is on the kinematics and mechanics of growth. Accordingly, the three first parts of the book are: Growth of curves and lamentary structure, Growth of surfaces, membranes, and shells, and Volumetric growth.

Applied Mathematics

Author: Alain Goriely
Editor: Oxford University Press
ISBN: 0198754043
File Size: 62,42 MB
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Mathematics is playing an increasingly important role in society and the sciences, enhancing our ability to use models and handle data. While pure mathematics is mostly interested in abstract structures, applied mathematics sits at the interface between this abstract world and the world in which we live. This area of mathematics takes its nourishment from society and science and, in turn, provides a unified way to understand problems arising in diverse fields. This Very Short Introduction presents a compact yet comprehensive view of the field of applied mathematics, and explores its relationships with (pure) mathematics, science, and engineering. Explaining the nature of applied mathematics, Alain Goriely discusses its early achievements in physics and engineering, and its development as a separate field after World War II. Using historical examples, current applications, and challenges, Goriely illustrates the particular role that mathematics plays in the modern sciences today and its far-reaching potential. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Continuum Modeling In Mechanobiology

Author: Larry A. Taber
Editor: Springer Nature
ISBN: 3030432092
File Size: 67,28 MB
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This book examines key theoretical tools that are currently used to develop mathematical models as an aid in understanding the biological response of cells and tissues to mechanical stimuli. Problems in growth and remodeling, tissue and organ development, and functional adaptation are all covered. Chapters on tensor analysis and nonlinear elasticity provide the necessary background for understanding the engineering theories that are currently used to solve challenges in mechanobiology. This is an ideal book for biomechanical engineers who work on problems in mechanobiology and tissue engineering.

New Trends In The Physics And Mechanics Of Biological Systems

Author: Martine Ben Amar
Editor: OUP Oxford
ISBN: 0191621242
File Size: 78,43 MB
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In July 2009, many experts in the mathematical modelling of biological sciences gathered in Les Houches for a 4-week summer school on the mechanics and physics of biological systems. The goal of the school was to present to students and researchers an integrated view of new trends and challenges in physical and mathematical aspects of biomechanics. While the scope for such a topic is very wide, we focused on problems where solid and fluid mechanics play a central role. The school covered both the general mathematical theory of mechanical biology in the context of continuum mechanics but also the specific modelling of particular systems in the biology of the cell, plants, microbes, and in physiology. These lecture notes are organised (as was the school) around five different main topics all connected by the common theme of continuum modelling for biological systems: Bio-fluidics, Bio-gels, Bio-mechanics, Bio-membranes, and Morphogenesis. These notes are not meant as a journal review of the topic but rather as a gentle tutorial introduction to the readers who want to understand the basic problematic in modelling biological systems from a mechanics perspective.

Exploring Mathematical Modeling In Biology Through Case Studies And Experimental Activities

Author: Rebecca Sanft
Editor: Academic Press
ISBN: 0128195967
File Size: 54,40 MB
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Exploring Mathematical Modeling in Biology through Case Studies and Experimental Activities provides supporting materials for courses taken by students majoring in mathematics, computer science or in the life sciences. The book's cases and lab exercises focus on hypothesis testing and model development in the context of real data. The supporting mathematical, coding and biological background permit readers to explore a problem, understand assumptions, and the meaning of their results. The experiential components provide hands-on learning both in the lab and on the computer. As a beginning text in modeling, readers will learn to value the approach and apply competencies in other settings. Included case studies focus on building a model to solve a particular biological problem from concept and translation into a mathematical form, to validating the parameters, testing the quality of the model and finally interpreting the outcome in biological terms. The book also shows how particular mathematical approaches are adapted to a variety of problems at multiple biological scales. Finally, the labs bring the biological problems and the practical issues of collecting data to actually test the model and/or adapting the mathematics to the data that can be collected. Presents a single volume on mathematics and biological examples, with data and wet lab experiences suitable for non-experts Contains three real-world biological case studies and one wet lab for application of the mathematical models Includes R code templates throughout the text, which are also available through an online repository, along with the necessary data files to complete all projects and labs

Mathematical Essays On Growth And The Emergence Of Form

Author: Peter L. Antonelli
Editor: University of Alberta
ISBN: 9780888640895
File Size: 30,49 MB
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Of interest to theoretical biologists, as well as mathematicians, physical scientists or anyone concerned with problems in growth, chemical ecology and the developmental biology of form, these essays on biological modelling by American, British and Canadian researchers provide an interesting geometric excursion to the frontiers of contemporary mathematical biology.

Mechanics Of Biological Tissue

Author: Gerhard A. Holzapfel
Editor: Springer Science & Business Media
ISBN: 354031184X
File Size: 59,10 MB
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Professor Jiji's broad teaching experience lead him to select the topics for this book to provide a firm foundation for convection heat transfer with emphasis on fundamentals, physical phenomena, and mathematical modelling of a wide range of engineering applications. Reflecting recent developments, this textbook is the first to include an introduction to the challenging topic of microchannels. The strong pedagogic potential of "Heat Convection" is enhanced by the following ancillary materials: Power Point lectures, Problem Solutions, Homework Facilitator, and Summary of Sections and Chapters.

Mathematical Biology

Author: James D. Murray
Editor: Springer Science & Business Media
ISBN: 9780387952239
File Size: 77,13 MB
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Mathematical Biology is a richly illustrated textbook in an exciting and fast growing field. Providing an in-depth look at the practical use of math modeling, it features exercises throughout that are drawn from a variety of bioscientific disciplines - population biology, developmental biology, physiology, epidemiology, and evolution, among others. It maintains a consistent level throughout so that graduate students can use it to gain a foothold into this dynamic research area.

Parabolic Equations In Biology

Author: Benoît Perthame
Editor: Springer
ISBN: 331919500X
File Size: 42,37 MB
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This book presents several fundamental questions in mathematical biology such as Turing instability, pattern formation, reaction-diffusion systems, invasion waves and Fokker-Planck equations. These are classical modeling tools for mathematical biology with applications to ecology and population dynamics, the neurosciences, enzymatic reactions, chemotaxis, invasion waves etc. The book presents these aspects from a mathematical perspective, with the aim of identifying those qualitative properties of the models that are relevant for biological applications. To do so, it uncovers the mechanisms at work behind Turing instability, pattern formation and invasion waves. This involves several mathematical tools, such as stability and instability analysis, blow-up in finite time, asymptotic methods and relative entropy properties. Given the content presented, the book is well suited as a textbook for master-level coursework.

Biological Growth And Spread

Author: Willi Jäger
Editor: Springer
ISBN:
File Size: 75,43 MB
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Biological Growth And Spread

Author: W. Jäger
Editor: Springer
ISBN: 9783540102571
File Size: 65,16 MB
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These Proceedings have been assembled from papers presented at the Conference on Models of Biological Growth and Spread, held at the German Cancer Research Centre Heidelberg and at the Institute of Applied Mathematics of the University of Heidelberg, July 16-21, 1979. The main theme of the conference was the mathematical representation of biolog ical populations with an underlying spatial structure. An important feature of such populations is that they and/or their individual com ponents may interact with each other. Such interactions may be due to external disturbances, internal regulatory factors or a combination of both. Many biological phenomena and processes including embryogenesis, cell growth, chemotaxis, cell adhesion, carcinogenesis, and the spread of an epidemic or of an advantageous gene can be studied in this con text. Thus, problems of particular importance in medicine (human and veterinary), agriculture, ecology, etc. may be taken into consideration and a deeper insight gained by utilizing (more) realistic mathematical models. Since the intrinsic biological mechanisms may differ considerably from each other, a great variety of mathematical approaches, theories and techniques is required. The aims of the conference were (i) To provide an overview of the most important biological aspects. (ii) To survey and analyse possible stochastic and deterministic approaches. (iii) To encourage new research by bringing together mathematicians interested in problems of a biological nature and scientists actively engaged in developing mathematical models in biology.

Mathematics In Population Biology

Author: Horst R. Thieme
Editor: Princeton University Press
ISBN: 0691187657
File Size: 79,61 MB
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Biological Growth And Spread

Author: Willi Jäger
Editor: Springer
ISBN:
File Size: 78,63 MB
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Mathematical Modeling Of Biological Systems Volume I

Author: Andreas Deutsch
Editor: Springer Science & Business Media
ISBN: 0817645586
File Size: 58,35 MB
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Volume I of this two-volume, interdisciplinary work is a unified presentation of a broad range of state-of-the-art topics in the rapidly growing field of mathematical modeling in the biological sciences. The chapters are thematically organized into the following main areas: cellular biophysics, regulatory networks, developmental biology, biomedical applications, data analysis and model validation. The work will be an excellent reference text for a broad audience of researchers, practitioners, and advanced students in this rapidly growing field at the intersection of applied mathematics, experimental biology and medicine, computational biology, biochemistry, computer science, and physics.

Mathematical Models In Biology

Author: Leah Edelstein-Keshet
Editor: SIAM
ISBN: 9780898719147
File Size: 40,80 MB
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Mathematical Models in Biology is an introductory book for readers interested in biological applications of mathematics and modeling in biology. A favorite in the mathematical biology community, it shows how relatively simple mathematics can be applied to a variety of models to draw interesting conclusions. Connections are made between diverse biological examples linked by common mathematical themes. A variety of discrete and continuous ordinary and partial differential equation models are explored. Although great advances have taken place in many of the topics covered, the simple lessons contained in this book are still important and informative. Audience: the book does not assume too much background knowledge--essentially some calculus and high-school algebra. It was originally written with third- and fourth-year undergraduate mathematical-biology majors in mind; however, it was picked up by beginning graduate students as well as researchers in math (and some in biology) who wanted to learn about this field.

Mathematical Models In Population Biology And Epidemiology

Author: Fred Brauer
Editor: Springer Science & Business Media
ISBN: 1475735162
File Size: 17,45 MB
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The goal of this book is to search for a balance between simple and analyzable models and unsolvable models which are capable of addressing important questions on population biology. Part I focusses on single species simple models including those which have been used to predict the growth of human and animal population in the past. Single population models are, in some sense, the building blocks of more realistic models -- the subject of Part II. Their role is fundamental to the study of ecological and demographic processes including the role of population structure and spatial heterogeneity -- the subject of Part III. This book, which will include both examples and exercises, is of use to practitioners, graduate students, and scientists working in the field.

Mathematical Biology Ii

Author: James D. Murray
Editor: Springer Science & Business Media
ISBN: 0387952284
File Size: 59,45 MB
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This richly illustrated third edition provides a thorough training in practical mathematical biology and shows how exciting mathematical challenges can arise from a genuinely interdisciplinary involvement with the biosciences. It has been extensively updated and extended to cover much of the growth of mathematical biology. From the reviews: ""This book, a classical text in mathematical biology, cleverly combines mathematical tools with subject area sciences."--SHORT BOOK REVIEWS

The Mathematics Behind Biological Invasions

Author: Mark A. Lewis
Editor: Springer
ISBN: 3319320432
File Size: 42,82 MB
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This book investigates the mathematical analysis of biological invasions. Unlike purely qualitative treatments of ecology, it draws on mathematical theory and methods, equipping the reader with sharp tools and rigorous methodology. Subjects include invasion dynamics, species interactions, population spread, long-distance dispersal, stochastic effects, risk analysis, and optimal responses to invaders. While based on the theory of dynamical systems, including partial differential equations and integrodifference equations, the book also draws on information theory, machine learning, Monte Carlo methods, optimal control, statistics, and stochastic processes. Applications to real biological invasions are included throughout. Ultimately, the book imparts a powerful principle: that by bringing ecology and mathematics together, researchers can uncover new understanding of, and effective response strategies to, biological invasions. It is suitable for graduate students and established researchers in mathematical ecology.