Tumor Models In Cancer Research

Author: Beverly A. Teicher
Editor: Springer Science & Business Media
ISBN: 1607619687
File Size: 73,90 MB
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The past 6 years since the first edition of this book have seen great progress in the development of genetically engineered mouse (GEM) models of cancer. These models are finding an important role in furthering our understanding of the biology of malignant disease. A comfortable position for GEM models in the routine conduct of screening for potential new therapeutics is coming more slowly but is coming. Increasing numbers of genetically engineered mice are available, some with conditional activation of oncogenes, some with multiple genetic changes providing mouse models that are moving closer to the human disease.
Tumor Models in Cancer Research
Language: en
Pages: 693
Authors: Beverly A. Teicher
Categories: Medical
Type: BOOK - Published: 2010-12-01 - Publisher: Springer Science & Business Media

The past 6 years since the first edition of this book have seen great progress in the development of genetically engineered mouse (GEM) models of cancer. These models are finding an important role in furthering our understanding of the biology of malignant disease. A comfortable position for GEM models in
Animal Models in Cancer Drug Discovery
Language: en
Pages: 470
Authors: Asfar Azmi, Ramzi M. Mohammad
Categories: Business & Economics
Type: BOOK - Published: 2019-04-16 - Publisher: Academic Press

Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on
The Nude Mouse in Oncology Research
Language: en
Pages: 350
Authors: Epie Boven
Categories: Medical
Type: BOOK - Published: 2018-01-18 - Publisher: CRC Press

The nude, athymic mouse (nu/nu) has become generally accepted as a valuable tool to study the biology and therapy of human cancers. This volume presents a critical review of the scientific merits of the animal as a recipient of human tumor tissue transplants. Important information is provided regarding biology, immunology,
Cancer Models
Language: en
Pages: 174
Authors: Michael Breitenbach, Jens Hoffmann
Categories: Medical
Type: BOOK - Published: 2019-02-05 - Publisher: Frontiers Media SA

Cancer research, like research on other diseases, highly depends on representative and reliable model systems. In the Research Topic “Cancer Models”, we collected original papers and review articles addressing the topic of tumor modeling from molecular biology, biochemistry, microorganisms, cells and organoids, fishes, animals and xenografts, up to computational cancer
Molecular Targeted Radiosensitizers
Language: en
Pages: 364
Authors: Henning Willers, Iris Eke
Categories: Medical
Type: BOOK - Published: 2020-08-10 - Publisher: Springer Nature

Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader with a comprehensive review of key pre-clinical research components required to identify effective radiosensitizing drugs. The book features discussions on the mechanisms and markers of clinical radioresistance, pre-clinical screening of targeted radiosensitizers, 3D radiation biology for studying radiosensitizers, in vivo determinations